Heterologous Protection against Asian Zika Virus Challenge in Rhesus Macaques
Table 1
Summary of virus stocks and culture history.
All Zika virus strains are the MR 766 prototype strain derived from the virus that was isolated from a sentinel rhesus monkey in Zika Forest, Entebbe, Uganda in April 1947[6]. All have undergone extensive mouse brain passage. The MR766 challenge stock was created for nonhuman primate natural history studies and was derived from the CDC virus. Challenge virus was prepared by inoculation of CDC virus onto a confluent monolayer of C6/36 mosquito cells and a clarified harvest of the culture medium was collected nine days post infection.
doi: https://doi.org/10.1371/journal.pntd.0005168.t001