Characterization of Lethal Zika Virus Infection in AG129 Mice
Fig 4
Comparative histological imaging of skeletal muscle and brain after mock infection and infection with ZIKV.
Musculature from the posterior rear limb of a ZIKV-infected mouse revealing nuclear rowing as well as degenerate muscle fibers and infiltrating inflammatory cells (A). Hippocampal section from a ZIKV-infected mouse revealing neutrophilic infiltration (B). Musculature from the same site in a mock-infected mouse (C) A section of hippocampus in the brain of mock-infected mouse (D). Scale bar, 20 μm. Data are representative of two independent experiments (n = 4 and 5).
doi: https://doi.org/10.1371/journal.pntd.0004682.g004