@article{discovery1516136, month = {October}, publisher = {NATURE PUBLISHING GROUP}, year = {2016}, journal = {Nature}, note = {This version is the author accepted manuscript. For information on re-use, please refer to the publisher's terms and conditions.}, number = {7624}, title = {A genomic history of Aboriginal Australia}, pages = {207--214}, volume = {538}, author = {Malaspinas, A-S and Westaway, MC and Muller, C and Sousa, VC and Lao, O and Alves, I and Bergstrom, A and Athanasiadis, G and Cheng, JY and Crawford, JE and Heupink, TH and Macholdt, E and Peischl, S and Rasmussen, S and Schiffels, S and Subramanian, S and Wright, JL and Albrechtsen, A and Barbieri, C and Dupanloup, I and Eriksson, A and Margaryan, A and Moltke, I and Pugach, I and Korneliussen, TS and Levkivskyi, IP and Moreno-Mayar, JV and Ni, S and Racimo, F and Sikora, M and Xue, Y and Aghakhanian, FA and Brucato, N and Brunak, S and Campos, PF and Clark, W and Ellingvag, S and Fourmile, G and Gerbault, P and Injie, D and Koki, G and Leavesley, M and Logan, B and Lynch, A and Matisoo-Smith, EA and McAllister, PJ and Mentzer, AJ and Metspalu, M and Migliano, AB and Murgha, L and Phipps, ME and Pomat, W and Reynolds, D and Ricaut, F-X and Siba, P and Thomas, MG and Wales, T and Wall, CM and Oppenheimer, SJ and Tyler-Smith, C and Durbin, R and Dortch, J and Manica, A and Schierup, MH and Foley, RA and Lahr, MM and Bowern, C and Wall, JD and Mailund, T and Stoneking, M and Nielsen, R and Sandhu, MS and Excoffier, L and Lambert, DM and Willerslev, E}, keywords = {Modern human dispersals, southeast-asia, neanderthal, ancestry, evolution, sequences, populations, europeans, admixture, african, Population genetics, Data processing, Anthropology, Genomics}, abstract = {The population history of Aboriginal Australians remains largely uncharacterized. Here we generate high-coverage genomes for 83 Aboriginal Australians (speakers of Pama-Nyungan languages) and 25 Papuans from the New Guinea Highlands. We find that Papuan and Aboriginal Australian ancestors diversified 25-40 thousand years ago (kya), suggesting pre-Holocene population structure in the ancient continent of Sahul (Australia, New Guinea and Tasmania). However, all of the studied Aboriginal Australians descend from a single founding population that differentiated {\texttt{\char126}}10-32 kya. We infer a population expansion in northeast Australia during the Holocene epoch (past 10,000 years) associated with limited gene flow from this region to the rest of Australia, consistent with the spread of the Pama-Nyungan languages. We estimate that Aboriginal Australians and Papuans diverged from Eurasians 51-72 kya, following a single out-of-Africa dispersal, and subsequently admixed with archaic populations. Finally, we report evidence of selection in Aboriginal Australians potentially associated with living in the desert.}, url = {http://doi.org/10.1038/nature18299}, issn = {0028-0836} }