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- La succinate semialdéhyde déshydrogénase est une oxydoréductase qui catalyse la réaction : semialdéhyde succinique + NAD+ + H2O succinate + NADH + 2 H+. Cette enzyme est présente chez des êtres vivants appartenant aux trois domaines du vivant : eucaryotes, bactéries et archées. Elle intervient dans la dégradation du γ-aminobutyrate chez l'homme, et une déficience en cette enzyme a de sérieuses conséquences sur la santé. Chez les bactéries, elle intervient également dans la conversion en succinate du semialdéhyde succinique, résultant de la métabolisation des cycles pyridine, ce qui fait le lien avec le cycle de Krebs. (fr)
- In enzymology, a succinate-semialdehyde dehydrogenase (SSADH) (EC 1.2.1.24) is an enzyme that catalyzes the chemical reaction succinate semialdehyde + NAD+ + H2O ⇌ succinate + NADH + 2 H+ The 3 substrates of this enzyme are succinate semialdehyde, NAD+, and H2O, whereas its 3 products are succinate, NADH, and H+. This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is succinate-semialdehyde:NAD+ oxidoreductase. Other names in common use include succinate semialdehyde dehydrogenase, succinic semialdehyde dehydrogenase, succinyl semialdehyde dehydrogenase, and succinate semialdehyde:NAD+ oxidoreductase. This enzyme participates in glutamate and butyrate metabolism. Succinate-semialdehyde dehydrogenase is found in organisms ranging across the tree of life from bacteria to humans. It is important in the degradation of γ-aminobutyric acid in humans, and deficiency of the enzyme causes serious health effects (succinic semialdehyde dehydrogenase deficiency). In bacteria, the enzyme is also involved in γ-aminobutyric acid degradation, but can be recruited to facilitate other functions, such as converting succinate-semialdehyde formed during fission of the pyridine ring to succinic acid for entry into the Krebs Cycle. (en)
- コハク酸セミアルデヒドデヒドロゲナーゼ（succinate-semialdehyde dehydrogenase）は、グルタミン酸と酪酸の代謝酵素の一つで、次の化学反応を触媒する酸化還元酵素である。 コハク酸セミアルデヒド + NAD+ + H2O コハク酸 + NADH + 2 H+ 反応式の通り、この酵素の基質はコハク酸セミアルデヒドとNAD+と水、生成物はコハク酸とNADHとH+である。 組織名はsuccinate-semialdehyde:NAD+ oxidoreductaseで、別名にsuccinate semialdehyde:NAD+ oxidoreductaseがある。 (ja)
- La succinato-semialdeide deidrogenasi è un enzima appartenente alla classe delle ossidoreduttasi, che catalizza la seguente reazione: succinato semialdeide + NAD+ + H2O ⇄ succinato + NADH + 2 H+ (it)
- コハク酸セミアルデヒドデヒドロゲナーゼ [NAD(P)+]（succinate-semialdehyde dehydrogenase [NAD(P)+]）は、グルタミン酸、チロシン、酪酸代謝酵素の一つで、次の化学反応を触媒する酸化還元酵素である。 コハク酸セミアルデヒド + NAD(P)+ + H2O コハク酸 + NAD(P)H + 2 H+ 反応式の通り、この酵素の基質はコハク酸セミアルデヒドとNAD(P)+と水、生成物はコハク酸とNAD(P)HとH+である。 組織名はsuccinate-semialdehyde:NAD(P)+ oxidoreductaseで、別名にsuccinate semialdehyde dehydrogenase (nicotinamide adenine dinucleotide (phosphate)), succinate-semialdehyde dehydrogenase [NAD(P)]がある。 (ja)
- La succinato-semialdeide deidrogenasi (NAD(P)+) è un enzima appartenente alla classe delle ossidoreduttasi, che catalizza la seguente reazione: succinato semialdeide + NAD(P)+ + H2O ⇄ succinato + NAD(P)H + 2 H+ (it)
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- 2922 (xsd:nonNegativeInteger)
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- Succinate semialdehyde dehydrogenase dodecamer, Human (en)
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- succinate-semialdehyde dehydrogenase (en)
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- コハク酸セミアルデヒドデヒドロゲナーゼ（succinate-semialdehyde dehydrogenase）は、グルタミン酸と酪酸の代謝酵素の一つで、次の化学反応を触媒する酸化還元酵素である。 コハク酸セミアルデヒド + NAD+ + H2O コハク酸 + NADH + 2 H+ 反応式の通り、この酵素の基質はコハク酸セミアルデヒドとNAD+と水、生成物はコハク酸とNADHとH+である。 組織名はsuccinate-semialdehyde:NAD+ oxidoreductaseで、別名にsuccinate semialdehyde:NAD+ oxidoreductaseがある。 (ja)
- La succinato-semialdeide deidrogenasi è un enzima appartenente alla classe delle ossidoreduttasi, che catalizza la seguente reazione: succinato semialdeide + NAD+ + H2O ⇄ succinato + NADH + 2 H+ (it)
- コハク酸セミアルデヒドデヒドロゲナーゼ [NAD(P)+]（succinate-semialdehyde dehydrogenase [NAD(P)+]）は、グルタミン酸、チロシン、酪酸代謝酵素の一つで、次の化学反応を触媒する酸化還元酵素である。 コハク酸セミアルデヒド + NAD(P)+ + H2O コハク酸 + NAD(P)H + 2 H+ 反応式の通り、この酵素の基質はコハク酸セミアルデヒドとNAD(P)+と水、生成物はコハク酸とNAD(P)HとH+である。 組織名はsuccinate-semialdehyde:NAD(P)+ oxidoreductaseで、別名にsuccinate semialdehyde dehydrogenase (nicotinamide adenine dinucleotide (phosphate)), succinate-semialdehyde dehydrogenase [NAD(P)]がある。 (ja)
- La succinato-semialdeide deidrogenasi (NAD(P)+) è un enzima appartenente alla classe delle ossidoreduttasi, che catalizza la seguente reazione: succinato semialdeide + NAD(P)+ + H2O ⇄ succinato + NAD(P)H + 2 H+ (it)
- La succinate semialdéhyde déshydrogénase est une oxydoréductase qui catalyse la réaction : semialdéhyde succinique + NAD+ + H2O succinate + NADH + 2 H+. Cette enzyme est présente chez des êtres vivants appartenant aux trois domaines du vivant : eucaryotes, bactéries et archées. Elle intervient dans la dégradation du γ-aminobutyrate chez l'homme, et une déficience en cette enzyme a de sérieuses conséquences sur la santé. (fr)
- In enzymology, a succinate-semialdehyde dehydrogenase (SSADH) (EC 1.2.1.24) is an enzyme that catalyzes the chemical reaction succinate semialdehyde + NAD+ + H2O ⇌ succinate + NADH + 2 H+ The 3 substrates of this enzyme are succinate semialdehyde, NAD+, and H2O, whereas its 3 products are succinate, NADH, and H+. In bacteria, the enzyme is also involved in γ-aminobutyric acid degradation, but can be recruited to facilitate other functions, such as converting succinate-semialdehyde formed during fission of the pyridine ring to succinic acid for entry into the Krebs Cycle. (en)
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- Succinate-semialdéhyde déshydrogénase (fr)
- Succinato-semialdeide deidrogenasi (NAD(P)+) (it)
- Succinato-semialdeide deidrogenasi (it)
- コハク酸セミアルデヒドデヒドロゲナーゼ (ja)
- コハク酸セミアルデヒドデヒドロゲナーゼ (NAD(P)+) (ja)
- Succinate-semialdehyde dehydrogenase (en)
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- succinate-semialdehyde dehydrogenase (en)
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