About: Nile red

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Nile red (also known as Nile blue oxazone) is a lipophilic stain. Nile red stains intracellular lipid droplets yellow. In most polar solvents, Nile red will not fluoresce; however, when in a lipid-rich environment, it can be intensely fluorescent, with varying colors from deep red (for polar membrane lipid) to strong yellow-gold emission (for neutral lipid in intracellular storages). The dye is highly solvatochromic and its emission and excitation wavelength both shift depending on solvent polarity and in polar media will hardly fluoresce at all.

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dbo:abstract
  • Nilrot, auch als Nilblau-Oxazon bezeichnet, ist ein lipophiler fluoreszierender Phenoxazin-Farbstoff. (de)
  • Nile red (also known as Nile blue oxazone) is a lipophilic stain. Nile red stains intracellular lipid droplets yellow. In most polar solvents, Nile red will not fluoresce; however, when in a lipid-rich environment, it can be intensely fluorescent, with varying colors from deep red (for polar membrane lipid) to strong yellow-gold emission (for neutral lipid in intracellular storages). The dye is highly solvatochromic and its emission and excitation wavelength both shift depending on solvent polarity and in polar media will hardly fluoresce at all. Nile red has applications in cell biology, where it can be used as a membrane dye which can be readily visualized using an epifluorescence microscope with excitation and emission wavelengths usually shared with red fluorescent protein. Nile red has also been used as part of a sensitive detection process for microplastics in bottled water. Additionally, nile red is a remarkable candidator in fabricating membrane for different sensors to detect environmental changes, such as taste, gas, pH, etc. In triglycerides (a neutral lipid), Nile red has an excitation maximum of about 515 nm (green), and emission maximum of about 585 nm (yellow-orange). In contrast, in phospholipids (polar lipids), Nile red has an excitation maximum of about 554 nm (green), and an emission maximum of about 638 nm (red). (en)
  • Czerwień Nilu – organiczny związek chemiczny, barwnik lipofilowy o zdolności do fluorescencji. Zarówno maksymalna emisja, jak i są silnie zależne od użytego rozpuszczalnika. Wyższa polarność rozpuszczalnika na ogół prowadzi do przesunięcia maksimum fluorescencji ku czerwieni i zmniejszenia wydajności kwantowej oraz czasu życia fluorescencji. (pl)
dbo:alternativeName
  • Nile red, Nile blue oxazone (en)
dbo:iupacName
  • 9-(Diethylamino)-5H-benzo[a]phenoxazin-5-one (en)
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  • 1574353 (xsd:integer)
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  • 7462 (xsd:nonNegativeInteger)
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  • 1120596095 (xsd:integer)
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  • Nile-red-3D-balls.png (en)
  • Nilrot.svg (en)
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  • 200 (xsd:integer)
  • 300 (xsd:integer)
dbp:othernames
  • Nile red, Nile blue oxazone (en)
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  • 9 (xsd:integer)
dbp:verifiedfields
  • changed (en)
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  • 476992673 (xsd:integer)
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  • Nilrot, auch als Nilblau-Oxazon bezeichnet, ist ein lipophiler fluoreszierender Phenoxazin-Farbstoff. (de)
  • Czerwień Nilu – organiczny związek chemiczny, barwnik lipofilowy o zdolności do fluorescencji. Zarówno maksymalna emisja, jak i są silnie zależne od użytego rozpuszczalnika. Wyższa polarność rozpuszczalnika na ogół prowadzi do przesunięcia maksimum fluorescencji ku czerwieni i zmniejszenia wydajności kwantowej oraz czasu życia fluorescencji. (pl)
  • Nile red (also known as Nile blue oxazone) is a lipophilic stain. Nile red stains intracellular lipid droplets yellow. In most polar solvents, Nile red will not fluoresce; however, when in a lipid-rich environment, it can be intensely fluorescent, with varying colors from deep red (for polar membrane lipid) to strong yellow-gold emission (for neutral lipid in intracellular storages). The dye is highly solvatochromic and its emission and excitation wavelength both shift depending on solvent polarity and in polar media will hardly fluoresce at all. (en)
rdfs:label
  • Nilrot (de)
  • Nile red (en)
  • Czerwień Nilu (pl)
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