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- In molecular biology, miR-130 microRNA precursor is a small non-coding RNA that regulates gene expression. This microRNA has been identified in mouse (MI0000156, MI0000408), and in human (MI0000448, MI0000748). miR-130 appears to be vertebrate-specific miRNA and has now been predicted or experimentally confirmed in a range of vertebrate species (MIPF0000034). Mature microRNAs are processed from the precursor stem-loop by the Dicer enzyme. In this case, the mature sequence is excised from the 3' arm of the hairpin. It has been found that miR-130 is upregulated in a type of cancer called hepatocellular carcinoma. It has been shown that miR-130a is expressed in the hematopoietic stem/progenitor cell compartment but not in mature blood cells. (en)
- miR-130（英語：miR-130 microRNA）是一类脊椎动物特有的miRNA，最初在小鼠基因组中，后在人类基因组中发现同源物，包括miR-130a和miR-130b。miR-130在多个肝細胞癌细胞系中高表达。 (zh)
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- 3771 (xsd:nonNegativeInteger)
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- Predicted secondary structure and sequence conservation of mir-130 (en)
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- mir-130 microRNA precursor family (en)
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| rdfs:comment
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- In molecular biology, miR-130 microRNA precursor is a small non-coding RNA that regulates gene expression. This microRNA has been identified in mouse (MI0000156, MI0000408), and in human (MI0000448, MI0000748). miR-130 appears to be vertebrate-specific miRNA and has now been predicted or experimentally confirmed in a range of vertebrate species (MIPF0000034). Mature microRNAs are processed from the precursor stem-loop by the Dicer enzyme. In this case, the mature sequence is excised from the 3' arm of the hairpin. It has been found that miR-130 is upregulated in a type of cancer called hepatocellular carcinoma. It has been shown that miR-130a is expressed in the hematopoietic stem/progenitor cell compartment but not in mature blood cells. (en)
- miR-130（英語：miR-130 microRNA）是一类脊椎动物特有的miRNA，最初在小鼠基因组中，后在人类基因组中发现同源物，包括miR-130a和miR-130b。miR-130在多个肝細胞癌细胞系中高表达。 (zh)
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- Mir-130 microRNA precursor family (en)
- MiR-130 (zh)
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