| dbo:abstract
|
- In enzymology, a leukotriene-E4 20-monooxygenase (EC 1.14.13.34) is an enzyme that catalyzes the chemical reaction (7E,9E,11Z,14Z)-(5S,6R)-6-(cystein-S-yl)-5-hydroxyicosa-7,9,11,14- tetraenoate + NADPH + H+ + O2 20-hydroxyleukotriene E4 + NADP+ + H2O The 5 substrates of this enzyme are , , NADPH, H+, and O2, whereas its 3 products are , NADP+, and H2O. This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derived from O2 with NADH or NADPH as one donor, and incorporation of one atom o oxygen into the other donor. The systematic name of this enzyme class is (7E,9E,11Z,14Z)-(5S,6R)-6-(cystein-S-yl)-5-hydroxyicosa-7,9,11,14-te traenoate,NADPH:oxygen oxidoreductase (20-hydroxylating). This enzyme is also called leukotriene-E4 omega-hydroxylase. This enzyme participates in arachidonic acid metabolism. (en)
- ロイコトリエン-E4-20-モノオキシゲナーゼ（leukotriene-E4 20-monooxygenase）は、アラキドン酸代謝酵素の一つで、次の化学反応を触媒する酸化還元酵素である。 ロイコトリエン-E4 + NADPH + H+ + O2 20-ロイコトリエン-E4 + NADP+ + H2O この酵素の基質はロイコトリエン-E4、NADPH、H+とO2で、生成物は20-ロイコトリエン-E4、NADP+とH2Oである。 組織名は(7E,9E,11Z,14Z)-(5S,6R)-6-(cystein-S-yl)-5-hydroxyicosa-7,9,11,14-tetraenoate,NADPH:oxygen oxidoreductase (20-hydroxylating)で、別名にleukotriene-E4 ω-hydroxylaseがある。 (ja)
- La leucotriene-E4 20-monoossigenasi è un enzima appartenente alla classe delle ossidoreduttasi, che catalizza la seguente reazione: (7E,9E,11Z,14Z)-(5S,6R)-6-(cistein-S-il)-5-idrossiicosa-7,9,11,14-tetra + NADPH + H+ + O2 ⇄ 20-idrossileucotriene E4 + NADP+ + H2O L'enzima agisce anche sul N-acetil-leucotriene E4, ma più lentamente. Non è uguale alla leucotriene-B4 20-monoossigenasi (numero EC 1.14.13.30). (it)
|
| rdfs:comment
|
- ロイコトリエン-E4-20-モノオキシゲナーゼ（leukotriene-E4 20-monooxygenase）は、アラキドン酸代謝酵素の一つで、次の化学反応を触媒する酸化還元酵素である。 ロイコトリエン-E4 + NADPH + H+ + O2 20-ロイコトリエン-E4 + NADP+ + H2O この酵素の基質はロイコトリエン-E4、NADPH、H+とO2で、生成物は20-ロイコトリエン-E4、NADP+とH2Oである。 組織名は(7E,9E,11Z,14Z)-(5S,6R)-6-(cystein-S-yl)-5-hydroxyicosa-7,9,11,14-tetraenoate,NADPH:oxygen oxidoreductase (20-hydroxylating)で、別名にleukotriene-E4 ω-hydroxylaseがある。 (ja)
- La leucotriene-E4 20-monoossigenasi è un enzima appartenente alla classe delle ossidoreduttasi, che catalizza la seguente reazione: (7E,9E,11Z,14Z)-(5S,6R)-6-(cistein-S-il)-5-idrossiicosa-7,9,11,14-tetra + NADPH + H+ + O2 ⇄ 20-idrossileucotriene E4 + NADP+ + H2O L'enzima agisce anche sul N-acetil-leucotriene E4, ma più lentamente. Non è uguale alla leucotriene-B4 20-monoossigenasi (numero EC 1.14.13.30). (it)
- In enzymology, a leukotriene-E4 20-monooxygenase (EC 1.14.13.34) is an enzyme that catalyzes the chemical reaction (7E,9E,11Z,14Z)-(5S,6R)-6-(cystein-S-yl)-5-hydroxyicosa-7,9,11,14- tetraenoate + NADPH + H+ + O2 20-hydroxyleukotriene E4 + NADP+ + H2O The 5 substrates of this enzyme are , , NADPH, H+, and O2, whereas its 3 products are , NADP+, and H2O. (en)
|
