About: Glufimet

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Glufimet (developmental code name RGPU-238), also known as dimethyl 3-phenylglutamate hydrochloride, is a derivative of glutamic acid (glutamate) which was developed in Russia and is related to the γ-aminobutyric acid (GABA) derivative phenibut (3-phenyl-GABA). It contains phenibut and glycine fragments in its chemical structure, has been described as a "GABA precursor", and is said to modulate the GABA and nitric oxide (NO) systems and to have antioxidant activity. It has been suggested that metabotropic glutamate receptors may also play a role in the mechanism of action of glufimet. Stress-protective effects have been described for glufimet in animals.

Property	Value
dbo:abstract	Glufimet (developmental code name RGPU-238), also known as dimethyl 3-phenylglutamate hydrochloride, is a derivative of glutamic acid (glutamate) which was developed in Russia and is related to the γ-aminobutyric acid (GABA) derivative phenibut (3-phenyl-GABA). It contains phenibut and glycine fragments in its chemical structure, has been described as a "GABA precursor", and is said to modulate the GABA and nitric oxide (NO) systems and to have antioxidant activity. It has been suggested that metabotropic glutamate receptors may also play a role in the mechanism of action of glufimet. Stress-protective effects have been described for glufimet in animals. (en)
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dbp:iupacName	dimethyl 2-amino-3-phenylpentanedioate;hydrochloride (en)
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dbp:synonyms	RGPU-238; Dimethyl 3-phenylglutamic acid hydrochloride; Dimethyl 3-phenylglutamate hydrochloride; 1,5-Dimethyl -2-amino-3-phenylpentanedioate hydrochloride (en)
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rdfs:comment	Glufimet (developmental code name RGPU-238), also known as dimethyl 3-phenylglutamate hydrochloride, is a derivative of glutamic acid (glutamate) which was developed in Russia and is related to the γ-aminobutyric acid (GABA) derivative phenibut (3-phenyl-GABA). It contains phenibut and glycine fragments in its chemical structure, has been described as a "GABA precursor", and is said to modulate the GABA and nitric oxide (NO) systems and to have antioxidant activity. It has been suggested that metabotropic glutamate receptors may also play a role in the mechanism of action of glufimet. Stress-protective effects have been described for glufimet in animals. (en)
rdfs:label	Glufimet (en)
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