About: Aureolysin

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Aureolysin (EC 3.4.24.29, protease III, staphylococcal metalloprotease, Staphylococcus aureus neutral proteinase) is an extracellular metalloprotease expressed by Staphylococcus aureus. This protease is a major contributor to the bacterium's virulence, or ability to cause disease, by cleaving host factors of the innate immune system as well as regulating S. aureus secreted toxins and cell wall proteins. To catalyze its enzymatic activities, aureolysin requires zinc and calcium which it obtains from the extracellular environment within the host.

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  • Aureolysin (EC 3.4.24.29, protease III, staphylococcal metalloprotease, Staphylococcus aureus neutral proteinase) is an extracellular metalloprotease expressed by Staphylococcus aureus. This protease is a major contributor to the bacterium's virulence, or ability to cause disease, by cleaving host factors of the innate immune system as well as regulating S. aureus secreted toxins and cell wall proteins. To catalyze its enzymatic activities, aureolysin requires zinc and calcium which it obtains from the extracellular environment within the host. (en)
  • オーレオリシン(Aureolysin、EC 3.4.24.29)は、金属プロテアーゼである。Staphylococcus aureus(黄色ブドウ球菌)に存在する。この酵素は、P1'位の疎水性残基の結合を選択的に、インスリンB鎖をテルモリシンと似たようなパターンで切断する反応を触媒する。またS. aureusのを活性化する。 (ja)
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  • 3.4.24.29
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  • 39333887 (xsd:integer)
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  • 3.400000 (xsd:double)
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  • 3 (xsd:integer)
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  • Aureolysin (en)
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  • Aureolysin (EC 3.4.24.29, protease III, staphylococcal metalloprotease, Staphylococcus aureus neutral proteinase) is an extracellular metalloprotease expressed by Staphylococcus aureus. This protease is a major contributor to the bacterium's virulence, or ability to cause disease, by cleaving host factors of the innate immune system as well as regulating S. aureus secreted toxins and cell wall proteins. To catalyze its enzymatic activities, aureolysin requires zinc and calcium which it obtains from the extracellular environment within the host. (en)
  • オーレオリシン(Aureolysin、EC 3.4.24.29)は、金属プロテアーゼである。Staphylococcus aureus(黄色ブドウ球菌)に存在する。この酵素は、P1'位の疎水性残基の結合を選択的に、インスリンB鎖をテルモリシンと似たようなパターンで切断する反応を触媒する。またS. aureusのを活性化する。 (ja)
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  • Aureolysin (en)
  • オーレオリシン (ja)
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  • Aureolysin (en)
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