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- Anti-Saccharomyces cerevisiae antibodies (ASCAs) are antibodies against antigens presented by the cell wall of the yeast Saccharomyces cerevisiae. These antibodies are directed against oligomannose sequences α-1,3 Man (α-1,2 Man α-1,2 Man)n (n = 1 or 2). ASCAs and perinuclear antineutrophil cytoplasmic antibodies (pANCAs) are the two most useful and often discriminating biomarkers for colitis. ASCA tends to recognize Crohn's disease more frequently, whereas pANCA tend to recognize ulcerative colitis. ASCA antibodies react to a yeast protein with mannans, a 200-kDa glycoprotein. (en)
- Les anticorps anti-Saccharomyces cerevisiæ (« Anti–Saccharomyces cerevisiae antibodies » ou ASCA, en anglais) sont un outil de diagnostic en médecine pour déterminer le type d'une maladie gastro-intestinale de type colite. Il s'agit d'anticorps dirigés vers des éléments de la paroi des cellules de Saccharomyces cerevisiae. Un résultat positif à ce test (présence d'anticorps) permet de montrer le caractère biotique de la maladie, comme dans le cas de la maladie de Crohn, et de la séparer des autres types d'étiologie, comme par exemple le caractère auto-immun comme dans le cas de la maladie cœliaque. (fr)
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- saccharomyces cerevisiae (en)
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- Saccharomyces cerevisiae (en)
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- Anti-Saccharomyces cerevisiae antibodies (ASCAs) are antibodies against antigens presented by the cell wall of the yeast Saccharomyces cerevisiae. These antibodies are directed against oligomannose sequences α-1,3 Man (α-1,2 Man α-1,2 Man)n (n = 1 or 2). ASCAs and perinuclear antineutrophil cytoplasmic antibodies (pANCAs) are the two most useful and often discriminating biomarkers for colitis. ASCA tends to recognize Crohn's disease more frequently, whereas pANCA tend to recognize ulcerative colitis. ASCA antibodies react to a yeast protein with mannans, a 200-kDa glycoprotein. (en)
- Les anticorps anti-Saccharomyces cerevisiæ (« Anti–Saccharomyces cerevisiae antibodies » ou ASCA, en anglais) sont un outil de diagnostic en médecine pour déterminer le type d'une maladie gastro-intestinale de type colite. Il s'agit d'anticorps dirigés vers des éléments de la paroi des cellules de Saccharomyces cerevisiae. (fr)
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- Anti–Saccharomyces cerevisiae antibody (en)
- Anticorps anti-Saccharomyces cerevisiae (fr)
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