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- Hydroxyprostaglandin dehydrogenase 15-(NAD) (the HUGO-approved symbol = HPGD; HGNC ID, HGNC:5154), also called 15-hydroxyprostaglandin dehydrogenase (NAD+), (EC 1.1.1.141), is an enzyme that catalyzes the following chemical reaction: (5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-13-enoate + NAD+ (5Z,13E)-11alpha-hydroxy-9,15-dioxoprost-13-enoate + NADH + H+ Thus, the two substrates of this enzyme are and NAD+, whereas its 3 products are , NADH, and H+. This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-13-enoate:NAD+ 15-oxidoreductase. Other names in common use include NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (type I), PGDH, 11alpha,15-dihydroxy-9-oxoprost-13-enoate:NAD+ 15-oxidoreductase, 15-OH-PGDH, 15-hydroxyprostaglandin dehydrogenase, 15-hydroxyprostanoic dehydrogenase, NAD+-specific 15-hydroxyprostaglandin dehydrogenase, prostaglandin dehydrogenase, and 15-hydroxyprostaglandin dehydrogenase (NAD+). (en)
- La 15-hydroxyprostaglandine déshydrogénase NAD+-dépendante est une oxydoréductase qui catalyse la réaction :Prostaglandine E2 + NAD+ (5Z,13E)-11α-hydroxy-9,15-dioxoprost-5,13-diénoate + NADH + H+. Cette enzyme intervient dans la dégradation de la prostaglandine E2. (fr)
- La 15-idrossiprostaglandina deidrogenasi (NAD+) è un enzima appartenente alla classe delle ossidoreduttasi, che catalizza la seguente reazione: (5Z,13E)-(15S)-11α,15-diidrossi-9-ossoprost-13- + NAD+ ⇄ (5Z,13E)-11α-idrossi-9,15-diossoprost-13-enoato + NADH + H+ L'enzima agisce sulla prostaglandina E2, F2α e B1, ma non sulla prostaglandina D2. (it)
- 15-ヒドロキシプロスタグランジンデヒドロゲナーゼ (NAD+)（15-hydroxyprostaglandin dehydrogenase (NAD+)）は、次の化学反応を触媒する酸化還元酵素である。 (5Z,13E)-(15S)-11α,15-ジヒドロキシ-9-オキソ-13-プロステン酸 + NAD+ (5Z,13E)-11α-ヒドロキシ-9,15-ジオキソ-13-プロステン酸 + NADH + H+ 反応式の通り、この酵素の基質は(5Z,13E)-(15S)-11α,15-ジヒドロキシ-9-オキソ-13-プロステン酸とNAD+、生成物はとNADHとH+である。 組織名は(5Z,13E,15S)-11α,15-dihydroxy-9-oxoprost-5,13-dienoate:NAD+15-oxidoreductaseで、別名に、
* NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (type I)
* PGDH
* 11α,15-dihydroxy-9-oxoprost-13-enoate:NAD+ 15-oxidoreductase
* 15-OH-PGDH
* 15-hydroxyprostaglandin dehydrogenase
* 15-hydroxyprostanoic dehydrogenase
* NAD+-specific 15-hydroxyprostaglandin dehydrogenase
* prostaglandin dehydrogenase
* 15-hydroxyprostaglandin dehydrogenase (NAD+)
* (5Z,13E)-(15S)-11α,15-dihydroxy-9-oxoprost-13-enoate:NAD+ 15-oxidoreductase がある。 (ja)
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| rdfs:comment
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- La 15-hydroxyprostaglandine déshydrogénase NAD+-dépendante est une oxydoréductase qui catalyse la réaction :Prostaglandine E2 + NAD+ (5Z,13E)-11α-hydroxy-9,15-dioxoprost-5,13-diénoate + NADH + H+. Cette enzyme intervient dans la dégradation de la prostaglandine E2. (fr)
- La 15-idrossiprostaglandina deidrogenasi (NAD+) è un enzima appartenente alla classe delle ossidoreduttasi, che catalizza la seguente reazione: (5Z,13E)-(15S)-11α,15-diidrossi-9-ossoprost-13- + NAD+ ⇄ (5Z,13E)-11α-idrossi-9,15-diossoprost-13-enoato + NADH + H+ L'enzima agisce sulla prostaglandina E2, F2α e B1, ma non sulla prostaglandina D2. (it)
- Hydroxyprostaglandin dehydrogenase 15-(NAD) (the HUGO-approved symbol = HPGD; HGNC ID, HGNC:5154), also called 15-hydroxyprostaglandin dehydrogenase (NAD+), (EC 1.1.1.141), is an enzyme that catalyzes the following chemical reaction: (5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-13-enoate + NAD+ (5Z,13E)-11alpha-hydroxy-9,15-dioxoprost-13-enoate + NADH + H+ Thus, the two substrates of this enzyme are and NAD+, whereas its 3 products are , NADH, and H+. (en)
- 15-ヒドロキシプロスタグランジンデヒドロゲナーゼ (NAD+)（15-hydroxyprostaglandin dehydrogenase (NAD+)）は、次の化学反応を触媒する酸化還元酵素である。 (5Z,13E)-(15S)-11α,15-ジヒドロキシ-9-オキソ-13-プロステン酸 + NAD+ (5Z,13E)-11α-ヒドロキシ-9,15-ジオキソ-13-プロステン酸 + NADH + H+ 反応式の通り、この酵素の基質は(5Z,13E)-(15S)-11α,15-ジヒドロキシ-9-オキソ-13-プロステン酸とNAD+、生成物はとNADHとH+である。 組織名は(5Z,13E,15S)-11α,15-dihydroxy-9-oxoprost-5,13-dienoate:NAD+15-oxidoreductaseで、別名に、 がある。 (ja)
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