High viral vector manufacturing costs are a major obstacle in gene therapy, but manufacturing viral vectors at scale doesn't have to mean higher costs. 💡 Cell enhancers such as Viral Sensitizers (VSE™) offer a powerful and flexible solution to rapidly optimize upstream viral vector yields without major CAPEX investments. Using VSE technology, you can: ✔ Enhance viral vector production efficiency without altering existing workflows. ✔ Reduce variability across batches, improving reproducibility at scale. ✔ Lower cost-per-dose by increasing vector yield. Curious about the data? See our solution in action: https://lnkd.in/dnEdkcRc #genetherapy #biomanufacturing #bioprocessing #viralvector #innovation
Virica Biotech
Biotechnology Research
Ottawa, Ontario 8,547 followers
Achieve higher yields, improve quality & scalability with Viral Sensitizers (VSE™)
About us
Cell and gene therapies, as well as viral vaccines, need higher production yields—and that's where we excel. We significantly increase yields by targeting the innate cellular defenses within production cells. These natural defenses, designed to combat foreign genetic material and inhibit viral replication, can hinder your process. Our solution is a unique panel small molecules which make up our Viral Sensitizer (VSETM) platform, which dampen cellular defenses. Using an innovative high-throughput screening process, we have developed a library of novel VSEs. Virica continues to leverage this advanced technology to pinpoint the most synergistic Viral Sensitizer molecules from our library, tailored to any virus or cell line. We customize formulations of these Viral Sensitizers to enhance virus yield in your manufacturing process or optimize the effectiveness of your viral therapies. The result is higher yields and improved quality, helping to reduce costs and improve patient access.
- Website
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http://www.viricabiotech.com
External link for Virica Biotech
- Industry
- Biotechnology Research
- Company size
- 11-50 employees
- Headquarters
- Ottawa, Ontario
- Type
- Privately Held
- Founded
- 2018
Locations
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Primary
7 Bayview Station Rd
Ottawa, Ontario K1Y 2C5, CA
Employees at Virica Biotech
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Lisa Kelly
Strategic Business Development Manager @ Virica Biotech | Biotechnology, Biopharmaceuticals
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Patrick Kerney
President at Belfield Investments Inc.
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Daniella Kranjac
Founding GP @Avant Bio | Founding Partner @Dynamk Capital
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Jean-Simon Diallo
CEO and Scientific Founder at Virica Biotech; Scientist, Cancer Therapeutics, Ottawa Hospital Research Institute (OHRI)
Updates
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We look forward to collaborating with Culture Biosciences for an upcoming webinar on leveraging cloud-connected bioreactors to enhance in-house capabilities for AAV and lentivirus development. Our speakers will showcase a next-generation bioreactor system that enables seamless workflows, external scalability, and accelerated, high-quality results. 📅 Secure your spot today! Register now: https://bit.ly/41IfXAV
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Virica Biotech reposted this
After an engaging day in Molsheim, France, our Head of Viral Vector, Daphné Bocciarelli, shares her reflections on the "Learn & Connect 2025 - Viral Gene Therapy" event, which focused on gene therapy manufacturing and quality control. 💡 What stood out? The event was packed with insightful talks and meaningful discussions, and it was a fantastic opportunity to connect with industry experts. There was significant interest in our partnership with Virica Biotech, particularly in how our ongoing scale-up work is advancing AAV manufacturing efficiency. Daphné’s key takeaways: 🔹 Regulatory challenges remain a barrier to adopting faster, more precise QC analytics for release testing and dosing assays. 🔹 Next-Generation Sequencing (NGS) is proving to be a powerful tool for assessing product quality at every stage of development. 🔹 Platform processes continue to divide opinion—while challenging, they are becoming an essential starting point for process development to meet clinical and investment milestones. 🔹 Could affinity columns be the next breakthrough for host cell protein (HCP) removal? 🔹 Automation is already transforming environmental monitoring, freeing up skilled scientists for higher-value tasks. A huge thank you to Merck Life Science for hosting this insightful event and to Virica Biotech for allowing us to showcase our collaborative project. Events like these are invaluable in advancing innovation in viral vector manufacturing. #GeneTherapy #AAV #ViralVectors #Bioprocessing #Automation #NGS #ProcessDevelopment #CellAndGeneTherapy #eXmoorPharma
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📽️ It's Friday, and that means we are back in another “Ask a Virologist” Segment! 💡 Liquid handlers play a big role in Virica’s automation and high throughput virology, significantly boosting lab productivity. But choosing the liquid handler for the job can be tricky. How do you know what liquid handler is right for the task? 👇 Our expert Glib Maznyi, breaks down the important aspects to consider when choosing a liquid handler for your automation needs. Got burning questions on liquid handlers or like to geek out with the benchtop tech? Shoot us a DM or drop it in the comments below! We’d love to know! Follow us to stay tuned for upcoming videos! #biomanufacturing #innovation #askavirologist
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📣 Advanced Therapies London is around the corner and we'd love to see you there! Meet with Azra Benson and Zeeshan Shaikh, to learn about how leveraging our Viral Sensitizers (VSEᵀᴹ) and Design of Experiments (DoE) -powered workflows unlock: ✔ Rapid viral vector production optimization. ✔ Robust increase in viral vector yield and quality. ✔ Significant reduction in long-term manufacturing COGS. 📣 Looking to drive up CGT manufacturing productivity and drive down COGS? A brief overview of our technology: https://lnkd.in/gu2m3RcX #biomanufacturing #innovation #AdvancedTherapies #cellandgenetherapy
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It's no secret that cell and gene therapy manufacturing is incredibly expensive. Some of the factors driving up costs include: - Limited vector yields per batch, increasing per-dose pricing - Need for higher titers to meet demand for commercial-scale production - Process inefficiencies leading to high COGS (Cost of Goods Sold) 💬 CGT manufacturing is complex and there is no "silver bullet" to improve efficiency and bring down COGs. A winning strategy involves a layered approach. Innovations such as stable producer cell lines, cell enhancer technologies and automation are essential to improve productivity and reduce costs. #biomanufacturing #innovation #cellandgenetherapy #viralvector #genetherapy #aavmanufacturing
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📣 eXmoor Pharma’s Head of Viral Vector, Daphné Bocciarelli, will present exciting collaboration data at 'Learn & Connect 2025 – Viral Gene Therapy' today in Molsheim, France. 💡 Daphné will share insights from our collaboration with eXmoor Pharma, focusing on optimizing AAV process performance by integrating Virica’s VSE™ technology with eXmoor’s AAV platform. The initiative aims to enhance AAV yields through scalable upstream improvements, accelerate development with a flexible, serotype-agnostic platform, and reduce costs using VSEs for manufacturing efficiency. Check out how VSEs can transform your AAV manufacturing: https://lnkd.in/dnEdkcRc #innovation #biomanufacturing #AAV
eXmoor pharma’s Head of Viral Vector, Daphné Bocciarelli, will be presenting at 'Learn & Connect 2025 – Viral Gene Therapy' today in Molsheim, France. 🎤 Her session, "Next generation AAV platforms: A case study looking at upstream process additives designed to enhance yield and purity of AAV processes", will explore new strategies for improving AAV manufacturing efficiency. As part of this, Daphné will be sharing insights from our collaboration with Virica Biotech, a project focused on optimising AAV process performance by integrating Virica’s Viral Sensitizer (VSETM) technology with eXmoor’s AAV platform process and analytical development expertise. This initiative aims to: 🔹 Enhance AAV yields through targeted and scalable upstream process improvements 🔹 Accelerate process development through a serotype agnostic flexible platform 🔹 Reduce production costs by using simple chemical additives to increase manufacturing efficiencies By combining eXmoor’s deep knowledge in AAV bioprocessing and high-performance platform with Virica’s innovative VSE technology, we are addressing key bottlenecks in AAV production and helping to accelerate the development of next-generation gene therapies. More info on today’s event: https://lnkd.in/e6S_KitH If you're attending, don’t miss Daphné’s session to learn more about how innovative upstream process solutions can transform AAV manufacturing. 💬 Want to discuss eXmoor’s AAV technology capabilities? Connect with Daphné Bocciarelli on LinkedIn or meet her at the event to explore how we can support your viral vector manufacturing needs. #AAV #ViralVectors #GeneTherapy #Bioprocessing #CellAndGeneTherapy #LifeSciences #Biopharma #ProcessDevelopment
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📣 Ask a Virologist is back with a behind-the-curtains peek at the tools and technology at Virica! High throughput assays are the core of what we do at Virica, and that's only possible with the right equipment! 👇 Check out Keara Sutherland, and Glib Maznyi, showcase liquid handlers and dispensers and how they power up our High Throughput Screening and DoE capabilities! Got burning questions or like to geek out with the benchtop tech? Shoot us a DM or drop it in the comments below! We’d love to know! Follow us to stay tuned for upcoming videos! #biomanufacturing #innovation #askavirologist
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Join Culture Biosciences & Virica Biotech for a webinar on how cloud-connected bioreactors enhance in-house facilities to streamline AAV and lentivirus development. Our experts will introduce a cutting-edge bioreactor system designed for seamless operations, external scalability, and faster, more reliable results. 📅 Don’t miss out—register now: https://bit.ly/4h0Cc9Q
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📣 We are excited to kick off our Ask a Virologist series for 2025! Curious how our tools supercharge viral vector production? We’ll break it down—fast! 💡 From precision liquid handlers to advanced analytics, at Virica, we use cutting-edge technology to boost efficiency, cut costs, and scale production. Stay tuned for a behind-the-scenes peek at the tools and technology at our facility! Got burning questions or like to geek out with the benchtop tech? Shoot us a DM or drop it in the comments below! We’d love to know! #biomanufacturing #innovation #askavirologist