Chen, Honglin, Charles, Philip D., Gu, Quan ORCID: https://orcid.org/0000-0002-1201-6734, Liberatori, Sabrina, Robertson, David L.
ORCID: https://orcid.org/0000-0001-6338-0221, Palmarini, Massimo
ORCID: https://orcid.org/0000-0001-7007-4070, Wilson, Sam J.
ORCID: https://orcid.org/0000-0002-6065-0895, Mohammed, Shabaz and Castello, Alfredo
ORCID: https://orcid.org/0000-0002-1499-4662
(2025)
Omics analyses uncover host networks defining virus-permissive and -hostile cellular states.
Molecular and Cellular Proteomics,
(doi: 10.1016/j.mcpro.2025.100966)
(In Press)
Bai, M. et al. (2024) Targeted degradation of zDHHC-PATs decreases substrate S -palmitoylation. PLoS ONE, 19(3), e0299665. (doi: 10.1371/journal.pone.0299665) (PMID:38512906) (PMCID:PMC10956751)
Lytras, S. et al. (2023) Resurrection of 2′-5′-oligoadenylate synthetase 1 (OAS1) from the ancestor of modern horseshoe bats blocks SARS-CoV-2 replication. PLoS Biology, 21(11), e3002398. (doi: 10.1371/journal.pbio.3002398) (PMID:38015855)
Pinto, R. M. et al. (2023) BTN3A3 evasion promotes the zoonotic potential of influenza A viruses. Nature, 619(7969), pp. 338-347. (doi: 10.1038/s41586-023-06261-8) (PMID:37380775)
Hardy, A. et al. (2023) The timing and magnitude of the type I interferon response are correlated with disease tolerance in arbovirus infection. mBio, 14(3), e0010123. (doi: 10.1128/mbio.00101-23) (PMID:37097030) (PMCID:PMC10294695)
Sugrue, E. et al. (2022) The apparent interferon resistance of transmitted HIV-1 is possibly a consequence of enhanced replicative fitness. PLoS Pathogens, 18(11), e1010973. (doi: 10.1371/journal.ppat.1010973) (PMID:36399512) (PMCID:PMC9718408)
Crozier, T. W.M. et al. (2022) Quantitative proteomic analysis of SARS-CoV-2 infection of primary human airway ciliated cells and lung epithelial cells demonstrates the effectiveness of SARS-CoV-2 innate immune evasion. Wellcome Open Research, 7, 224. (doi: 10.12688/wellcomeopenres.17946.1) (PMID:36483314) (PMCID:PMC9706147)
Bamford, Connor G.C., Aranday-Cortes, Elihu ORCID: https://orcid.org/0000-0003-2637-2307, Sanchez-Velazquez, Ricardo, Mullan, Catrina, Kohl, Alain
ORCID: https://orcid.org/0000-0002-1523-9458, Patel, Arvind H.
ORCID: https://orcid.org/0000-0003-4600-2047, Wilson, Sam J.
ORCID: https://orcid.org/0000-0002-6065-0895 and McLauchlan, John
ORCID: https://orcid.org/0000-0003-2217-9948
(2022)
A human and rhesus macaque interferon-stimulated gene screen shows that over-expression of ARHGEF3/XPLN inhibits replication of hepatitis C virus and other flavivirids.
Viruses, 14(8),
1655.
(doi: 10.3390/v14081655)
(PMID:36016278)
(PMCID:PMC9414520)
Fielding, C. A. et al. (2022) SARS-CoV-2 host-shutoff impacts innate NK cell functions, but antibody-dependent NK activity is strongly activated through non-spike antibodies. eLife, 11, e74489. (doi: 10.7554/elife.74489) (PMID:35587364) (PMCID:PMC9239683)
Galão, Rui Pedro, Wilson, Harry, Schierhorn, Kristina L., Debeljak, Franka, Bodmer, Bianca S., Goldhill, Daniel, Hoenen, Thomas, Wilson, Sam J. ORCID: https://orcid.org/0000-0002-6065-0895, Swanson, Chad M. and Neil, Stuart J. D.
(2022)
TRIM25 and ZAP target the Ebola virus ribonucleoprotein complex to mediate interferon-induced restriction.
PLoS Pathogens, 18(5),
e1010530.
(doi: 10.1371/journal.ppat.1010530)
(PMID:35533151)
(PMCID:PMC9119685)
Wickenhagen, A. et al. (2021) A prenylated dsRNA sensor protects against severe COVID-19. Science, 374(6567), eabj3624. (doi: 10.1126/science.abj3624) (PMID:34581622) (PMCID:PMC7612834)
Shaw, A. E. et al. (2021) The antiviral state has shaped the CpG composition of the vertebrate interferome to avoid self-targeting. PLoS Biology, 19(9), e3001352. (doi: 10.1371/journal.pbio.3001352) (PMID:34491982) (PMCID:PMC8423302)
Szemiel, A. M. et al. (2021) In vitro selection of Remdesivir resistance suggests evolutionary predictability of SARS-CoV-2. PLoS Pathogens, 17(9), e1009929. (doi: 10.1371/journal.ppat.1009929) (PMID:34534263) (PMCID:PMC8496873)
Rihn, S. J. et al. (2021) A plasmid DNA-launched SARS-CoV-2 reverse genetics system and coronavirus toolkit for COVID-19 research. PLoS Biology, 19(2), e3001091. (doi: 10.1371/journal.pbio.3001091) (PMID:33630831) (PMCID:PMC7906417)
Ruddell, Stuart, Sugrue, Elena ORCID: https://orcid.org/0000-0001-5014-9522, Memarzadeh, Sarah, Hellam, Lorna Mae, Wilson, Sam
ORCID: https://orcid.org/0000-0002-6065-0895 and France, David
ORCID: https://orcid.org/0000-0002-5409-3316
(2021)
Synthesis, enantiomeric resolution and biological evaluation of HIV capsid inhibition activity for racemic, (S)- and (R)-PF74.
Molecules, 26(13),
3919.
(doi: 10.3390/molecules26133919)
(PMID:34206893)
(PMCID:PMC8272108)
Lin, Yao-Tang, Chiweshe, Stephen, McCormick, Dominique, Raper, Anna, Wickenhagen, Arthur, DeFillipis, Victor, Gaunt, Eleanor, Simmonds, Peter, Wilson, Sam J. ORCID: https://orcid.org/0000-0002-6065-0895 and Grey, Finn
(2020)
Human cytomegalovirus evades ZAP detection by suppressing CpG dinucleotides in the major immediate early 1 gene.
PLoS Pathogens, 16(9),
e1008844.
(doi: 10.1371/journal.ppat.1008844)
(PMID:32886716)
(PMCID:PMC7498042)
Rihn, S. J. et al. (2019) TRIM69 inhibits vesicular stomatitis Indiana virus (VSIV). Journal of Virology, 93(20), e00951-19. (doi: 10.1128/JVI.00951-19) (PMID:31375575)
Dennis, Tristan P.W., Souza, William Marciel de, Marsile-Medun, Soledad, Singer, Joshua B., Wilson, Sam J. ORCID: https://orcid.org/0000-0002-6065-0895 and Gifford, Robert J.
ORCID: https://orcid.org/0000-0003-4028-9884
(2019)
The evolution, distribution and diversity of endogenous circoviral elements in vertebrate genomes.
Virus Research, 262,
pp. 15-23.
(doi: 10.1016/j.virusres.2018.03.014)
(PMID:29601845)
(PMCID:PMC6372831)
Dennis, Tristan P.W., Flynn, Peter J., Souza, William Marciel de, Singer, Joshua B., Moreau, Corrie S., Wilson, Sam J. ORCID: https://orcid.org/0000-0002-6065-0895 and Gifford, Robert J.
ORCID: https://orcid.org/0000-0003-4028-9884
(2018)
Insights into circovirus host range from the genomic fossil record.
Journal of Virology, 92(16),
e00145-18.
(doi: 10.1128/JVI.00145-18)
(PMID:29875243)
(PMCID:PMC6069186)
Feng, J. et al. (2018) Interferon-stimulated gene (ISG)-expression screening reveals the specific antibunyaviral activity of ISG20. Journal of Virology, 92(13), e02140-17. (doi: 10.1128/JVI.02140-17) (PMID:29695422) (PMCID:PMC6002717)
Shaw, A. E. et al. (2017) Fundamental properties of the mammalian innate immune system revealed by multispecies comparison of type I interferon responses. PLoS Biology, 15(12), e2004086. (doi: 10.1371/journal.pbio.2004086) (PMID:29253856) (PMCID:PMC574750)
Rihn, Suzannah J. ORCID: https://orcid.org/0000-0001-9495-4056, Foster, Toshana L., Busnadiego, Idoia, Aziz, Muhamad Afiq Bin, Hughes, Joseph
ORCID: https://orcid.org/0000-0003-2556-2563, Neil, Stuart J.D. and Wilson, Sam J.
ORCID: https://orcid.org/0000-0002-6065-0895
(2017)
The envelope gene of transmitted HIV-1 resists a late interferon gamma-induced block.
Journal of Virology, 91(7),
e02254-16.
(doi: 10.1128/JVI.02254-16)
(PMID:28100611)
(PMCID:PMC5355616)
Terry, Anne, Kilbey, Anna, Naseer, Asif, Levy, Laura S., Ahmad, Shamim, Watts, Ciorsdaidh, Mackay, Nancy, Cameron, Ewan ORCID: https://orcid.org/0000-0001-8311-1491, Wilson, Sam
ORCID: https://orcid.org/0000-0002-6065-0895 and Neil, James C.
ORCID: https://orcid.org/0000-0003-4447-8279
(2017)
Barriers to infection of human cells by feline leukemia virus: insights into resistance to zoonosis.
Journal of Virology, 91(5),
e02119-16.
(doi: 10.1128/JVI.02119-16)
(PMID:28031367)
(PMCID:PMC5309941)
Kane, Melissa, Zang, Trinity M., Rihn, Suzannah J. ORCID: https://orcid.org/0000-0001-9495-4056, Zhang, Fengwen, Kueck, Tonya, Alim, Mudathir, Schoggins, John, Rice, Charles M., Wilson, Sam J.
ORCID: https://orcid.org/0000-0002-6065-0895 and Bieniasz, Paul D.
(2016)
Identification of interferon-stimulated genes with antiretroviral activity.
Cell Host and Microbe, 20(3),
pp. 392-405.
(doi: 10.1016/j.chom.2016.08.005)
(PMID:27631702)
(PMCID:PMC5026698)
Dittmann, M. et al. (2015) A Serpin shapes the extracellular environment to prevent influenza A virus maturation. Cell, 160(4), pp. 631-643. (doi: 10.1016/j.cell.2015.01.040) (PMID:25679759) (PMCID:PMC4328142)
Rihn, Suzannah J. ORCID: https://orcid.org/0000-0001-9495-4056, Hughes, Joseph
ORCID: https://orcid.org/0000-0003-2556-2563, Wilson, Sam J.
ORCID: https://orcid.org/0000-0002-6065-0895 and Bieniasz, Paul D.
(2015)
Uneven genetic robustness of HIV-1 integrase.
Journal of Virology, 89(1),
pp. 552-567.
(doi: 10.1128/JVI.02451-14)
Busnadiego, I. et al. (2014) Host and viral determinants of Mx2 antiretroviral activity. Journal of Virology, 88(14), pp. 7738-7752. (doi: 10.1128/JVI.00214-14) (PMID:24760893) (PMCID:PMC4097781)
Kane, M. et al. (2013) MX2 is an interferon-induced inhibitor of HIV-1 infection. Nature, 502(7472), pp. 563-566. (doi: 10.1038/nature12653)
Soll, Steven J., Wilson, Sam J. ORCID: https://orcid.org/0000-0002-6065-0895, Kutluay, Sebla B., Hatziioannou, Theodora and Bieniasz, Paul D.
(2013)
Assisted evolution enables HIV-1 to overcome a high trim5α-imposed genetic barrier to rhesus macaque tropism.
PLoS Pathogens, 9(9),
e1003667.
(doi: 10.1371/journal.ppat.1003667)
(PMID:24086139)
(PMCID:PMC3784476)
Rihn, S.J. ORCID: https://orcid.org/0000-0001-9495-4056, Wilson, S.J.
ORCID: https://orcid.org/0000-0002-6065-0895, Loman, N.J., Alim, M., Bakker, S.E., Bhella, D.
ORCID: https://orcid.org/0000-0003-2096-8310, Gifford, R.J., Rixon, F.J. and Bieniasz, P.D.
(2013)
Extreme genetic fragility of the HIV-1 capsid.
PLoS Pathogens, 9(6),
e1003461.
(doi: 10.1371/journal.ppat.1003461)
(PMID:23818857)
(PMCID:PMC3688543)
Wilson, Sam J. ORCID: https://orcid.org/0000-0002-6065-0895, Schoggins, John W., Zang, Trinity, Kutluay, Sebla B., Jouvenet, Nolwenn, Alim, Mudathir A., Bitzegeio, Julia, Rice, Charles M. and Bieniasz, Paul D.
(2012)
Inhibition of HIV-1 particle assembly by 2′,3′-cyclic-nucleotide 3′-phosphodiesterase.
Cell Host and Microbe, 12(4),
pp. 585-597.
(doi: 10.1016/j.chom.2012.08.012)
(PMID:23084924)
(PMCID:PMC3498451)
Yadav, S.S., Wilson, S.J. ORCID: https://orcid.org/0000-0002-6065-0895 and Bieniasz, P.D.
(2012)
A facile quantitative assay for viral particle genesis reveals cooperativity in virion assembly and saturation of an antiviral protein.
Virology, 429(2),
pp. 155-162.
(doi: 10.1016/j.virol.2012.04.008)
Schoggins, J.W., Wilson, S.J. ORCID: https://orcid.org/0000-0002-6065-0895, Panis, M., Murphy, M., Jones, C.T., Bieniasz, P.D. and Rice, C.M.
(2011)
A diverse range of gene products are effectors of the type I interferon antiviral response.
Nature, 472(7344),
pp. 481-485.
(doi: 10.1038/nature09907)
(PMID:21478870)
(PMCID:PMC3409588)
Zhang, F., Zang, T., Wilson, S.J. ORCID: https://orcid.org/0000-0002-6065-0895, Johnson, M.C. and Bieniasz, P.D.
(2011)
Clathrin facilitates the morphogenesis of retrovirus particles.
PLoS Pathogens, 7(6),
e1002119.
(doi: 10.1371/journal.ppat.1002119)
Pardieu, C., Vigan, R., Wilson, S.J. ORCID: https://orcid.org/0000-0002-6065-0895, Calvi, A., Zang, T., Bieniasz, P., Kellam, P., Towers, G.J. and Neil, S.J.D.
(2010)
The RING-CH ligase K5 antagonizes restriction of KSHV and HIV-1 particle release by mediating ubiquitin-dependent endosomal degradation of tetherin.
PLoS Pathogens, 6(4),
e1000843.
(doi: 10.1371/journal.ppat.1000843)
Price, A. J., Marzetta, F., Lammers, M., Ylinen, L.M.J., Schaller, T., Wilson, S.J. ORCID: https://orcid.org/0000-0002-6065-0895, Towers, G.J. and James, L.C.
(2009)
Active site remodeling switches HIV specificity of antiretroviral TRIMCyp.
Nature Structural and Molecular Biology, 16(10),
pp. 1036-42.
(doi: 10.1038/nsmb.1667)
Dalton-Griffin, L., Wilson, S.J. ORCID: https://orcid.org/0000-0002-6065-0895 and Kellam, P.
(2009)
X-box binding protein 1 contributes to induction of the Kaposi's sarcoma-associated herpesvirus lytic cycle under hypoxic conditions.
Journal of Virology, 83(14),
pp. 7202-7209.
(doi: 10.1128/JVI.00076-09)
Zaitseva, L., Cherepanov, P., Leyens, L., Wilson, S.J. ORCID: https://orcid.org/0000-0002-6065-0895, Rasaiyaah, J. and Fassati, A.
(2009)
HIV-1 exploits importin 7 to maximize nuclear import of its DNA genome.
Retrovirology, 6(11),
(doi: 10.1186/1742-4690-6-11)
Zhang, F., Wilson, S.J. ORCID: https://orcid.org/0000-0002-6065-0895, Landford, W.C., Virgen, B., Gregory, D., Johnson, M.C., Munch, J., Kirchoff, F., Bieniasz, P.D. and Hatziioannou, T.
(2009)
Nef proteins from simian immunodeficiency viruses are tetherin antagonists.
Cell Host and Microbe, 6(1),
pp. 54-67.
(doi: 10.1016/j.chom.2009.05.008)
Wilson, S.J. ORCID: https://orcid.org/0000-0002-6065-0895, Webb, B.L.J., Maplanka, C., Newman, R.M., Verschoor, E.J., Heeney, J.L. and Towers, G.J.
(2008)
Rhesus macaque TRIM5 alleles have divergent antiretroviral specificities.
Journal of Virology, 82(14),
pp. 7243-7247.
(doi: 10.1128/JVI.00307-08)
Wilson, S.J. ORCID: https://orcid.org/0000-0002-6065-0895, Webb, B.L.J., Ylinen, L.M., Verschoor, E., Heeney, J.L. and Towers, G.J.
(2008)
Independent evolution of an antiviral TRIMCyp in rhesus macaques.
Proceedings of the National Academy of Sciences of the United States of America, 105(9),
3557 -3562.
(doi: 10.1073/pnas.0709003105)
Wilson, S.J. ORCID: https://orcid.org/0000-0002-6065-0895, Tsao, E.H., Webb, B.L.J., Ye, H., Dalton-Griffin, L., Tsantoulas, C., Gale, C.V., Du, M.-Q., Whitehouse, A. and Kellam, P.
(2007)
X box binding protein XBP-1s transactivates the Kaposi's sarcoma-associated herpesvirus (KSHV) ORF50 promoter, linking plasma cell differentiation to KSHV reactivation from latency.
Journal of Virology, 81(24),
pp. 13578-13586.
(doi: 10.1128/JVI.01663-07)
Clements, M.O., Godfrey, A., Crossley, J., Wilson, S.J. ORCID: https://orcid.org/0000-0002-6065-0895, Takeuchi, Y. and Boshoff, C.
(2006)
Lentiviral manipulation of gene expression in human adult and embryonic stem cells.
Tissue Engineering, 12(7),
pp. 1741-1751.
(doi: 10.1089/ten.2006.12.1741)
Ylinen, L.M.J., Keckesova, Z., Wilson, S.J. ORCID: https://orcid.org/0000-0002-6065-0895, Ranasinghe, S. and Towers, G.J.
(2005)
Differential restriction of human immunodeficiency virus type 2 and simian immunodeficiency virus SIVmac by TRIM5alpha alleles.
Journal of Virology, 79(18),
pp. 11580-11587.
(doi: 10.1128/JVI.79.18.11580-11587.2005)