R.J. Palacio was inspired to write the book after taking her son out for ice cream, where they saw a child with Treacher Collins Syndrome. Her son cried at the sight of this boy. This story is used in a scene from the film, where Jack Will's (Noah Jupe) mother is reminding him why it's essential to make Auggie feel welcome.
Auggie's facial deformity is called Mandibulofacial Dysostosis (MFD), also known as Treacher Collins Syndrome.
Jacob Tremblay and his family went to the Children's Craniofacial Association retreat, where he got to meet and befriend children with Treacher Collins syndrome, the same syndrome that Auggie has.
Audiences often don't realize that every inch of Jacob Tremblay, from head to shoulders, was covered in silicone prosthetics, including dental prosthetics, contact lenses, and a wig to complete the look. Arjen Tuiten. However, the team also had to ensure everything was flexible to contend with the reality that Jacob was still a growing boy. "What an amazing actor. The other kids are great too, but Jacob is something special," said Tuiten. "Even if he never does prosthetic makeup again, this character will have a special place in his heart. He'll go on to be famous and handsome and, you know, all those things, but 'Auggie' will forever be immortalized on the screen. He'll outlive us all."
The bicycle that August (Jacob Tremblay) is riding in the film is the same bicycle that Elliott is seen riding in E.T., l'extra-terrestre (1982).
R.J. Palacio: During the graduation scene, as one of the audience members; she can be seen sitting next to Jack Will's mother (Nicole Oliver) behind the Pullmans.