The film was based on the Broadway play of the same name by Henry Ephron and his wife and partner Phoebe Ephron, who were inspired by their real-life correspondence with their college-age daughter, the eventual novelist, screenwriter and film director Nora Ephron.
During the costume party on the boat, many women are dressed as Cleopatra. Twentieth Century Fox released the movie Cleopatra starring Elizabeth Taylor later in 1963. Sandra's Dee's hair is styled exactly like Elizabeth Taylor's.
The original Broadway production of the musical "Take Her, She's Mine" opened at the Biltmore Theater on December 21, 1961 and ran for 404 performances. Art Carney, Audrey Meadows "Honeymooners" co-star, originated the role of Frank Michaelson.