- On May 12, 2014, Sherri filed for divorce from her second husband of three years, Lamar Sally after discovering multiple infidelities and him living a double life. In social media posts, she has referred to him as a "con artist.".
- Initially, Shepherd was expecting twins, but the girl died in utero, and she ended up in giving birth only a boy, Jeffrey, 3 months prematurely.
- Sherri and her son, Jeffrey Tarpley Jr., share the same birthday.
- Her debut book, "Permission Slips: Every Women's Guide to Give Herself a Break" was released in 2009. Her second book, "Plan D: How to Lose Weight and Beat Diabetes" was released in 2013 and made The New York Times Bestsellers list.
- Her first stand-up comedy CD/DVD, "No Refund, No Exchange" was released in 2006. Her second comedy special "It's My Time To Talk" was taped in Arizona and aired on the EPIX channel in 2013.
- Has 2 sons: Jeffrey Tarpley Jr. (b. April 22, 2005) with 1st ex-husband, Jeff Tarpley & Lamar Sally Jr. (b. August 5, 2014) with 2nd ex-husband, Lamar Sally.
- She was born in Chicago and attended Winston Churchill Elementary School and Eisenhower Junior High School of Community Consolidated School District 54 and Hoffman Estates High School of District 211.
- She appeared in the May 1, 2009 edition of Smackdown as a valet to MVP.
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