Selenis Leyva, George Lopez, and Nicole Weingart in Lopez vs. Lopez (2022)

Elpidia Carrillo, Damián Alcázar, George Lopez, Xolo Maridueña, and Belissa Escobedo in Blue Beetle (2023)

George Lopez and Jimmie 'JJ' Walker in George Lopez (2002)

Conan O'Brien and George Lopez in Conan (2010)

David Arquette, Kristin Davis, George Lopez, and Cayden Boyd in The Adventures of Sharkboy and Lavagirl 3-D (2005)

George Lopez, Cayden Boyd, Taylor Lautner, and Taylor Dooley in The Adventures of Sharkboy and Lavagirl 3-D (2005)

M.C. Gainey and George Lopez in Lopez (2016)

Beth Broderick, M.C. Gainey, and George Lopez in Lopez (2016)

Beth Broderick and George Lopez in Lopez (2016)

George Lopez and Jenna Macari in Lopez (2016)

Jacqueline Obradors, George Lopez, and Anthony 'Citric' Campos in Lopez (2016)

George Lopez, Karlee Eldridge, and Markie Farnsley in Lopez (2016)

Federico Dordei, George Lopez, and Anthony 'Citric' Campos in Lopez (2016)

George Lopez, Chris Dotson, and Jesse Einstein

Luke Wilson, Adriana Barraza, Cheryl Hines, George Lopez, Radha Mitchell, and Morgan Lily in Henry Poole Is Here (2008)

George Lopez and Jane Lynch in Mr. Troop Mom (2008)

George Lopez, Taylor Lautner, and Taylor Dooley in The Adventures of Sharkboy and Lavagirl 3-D (2005)