- Son of Alan Arkin and his first wife Jeremy Yaffe.
- Was nominated for Broadway's 1991 Tony Award as Best Actor (Featured Role - Play) for "I Hate Hamlet."
- Father Alan Arkin and daughter Molly have guest-starred on his TV series, Chicago Hope (1994).
- He is of Russian Jewish and German Jewish descent.
- Has two children, Molly (b. January 22, 1987) and Emmet.
- One of the three actors (along with Bruce Willis and Dennis Dugan) whom producer Glenn Gordon Caron seriously considered for the role of "David Addison" on Moonlighting (1985).
- Provided voice acting for the 1983 NPR radio dramatization of "Star Wars". He played "Fixer", one of Luke Skywalker's childhood friends.
- Brother of Matthew Arkin.
- Half-brother of Anthony Arkin.
- Stepmother is Suzanne Newlander Arkin.
- Has directed one Emmy Award-winning performance: Kelsey Keel in My Louisiana Sky (2001).
- Former stepson of Barbara Dana.
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