James Marsden and Jack Black in The D Train (2015)

James Marsden and Michelle Monaghan in The Best of Me (2014)

James Marsden, Michelle Monaghan, Liana Liberato, and Luke Bracey in The Best of Me (2014)

Nick Stahl, Katie Holmes, and James Marsden in Disturbing Behavior (1998)

Alexander Skarsgård and James Marsden in Straw Dogs (2011)

Cameron Diaz, Frank Langella, and James Marsden in The Box (2009)

Michelle Pfeiffer, Christopher Walken, Queen Latifah, Amanda Bynes, James Marsden, Elijah Kelley, Brittany Snow, Zac Efron, and Nikki Blonsky in Hairspray (2007)

Katherine Heigl, James Marsden, and Edward Burns in 27 Dresses (2008)

Famke Janssen, Halle Berry, Patrick Stewart, James Marsden, Ian McKellen, Rebecca Romijn, Hugh Jackman, and Ray Park in X-Men (2000)

Michelle Pfeiffer, John Travolta, Christopher Walken, Queen Latifah, Amanda Bynes, Allison Janney, James Marsden, Brittany Snow, Zac Efron, and Nikki Blonsky in Hairspray (2007)

Michelle Pfeiffer, John Travolta, Christopher Walken, Queen Latifah, Amanda Bynes, James Marsden, Elijah Kelley, Brittany Snow, Zac Efron, and Nikki Blonsky in Hairspray (2007)

Michelle Pfeiffer, John Travolta, Christopher Walken, Queen Latifah, Amanda Bynes, James Marsden, Brittany Snow, Zac Efron, and Nikki Blonsky in Hairspray (2007)

James Marsden and Tika Sumpter in Sonic the Hedgehog 3 (2024)

James Marsden and Antoni Porowski in No Taste Like Home with Antoni Porowski (2025)

James Marsden, Maria Russell, and Cassandra Blair in Jury Duty (2023)

Jerry Seinfeld, James Marsden, Thomas Lennon, Adrian Martinez, Bobby Moynihan, and Jack McBrayer in Unfrosted (2024)

James Marsden, Maddie, Tika Sumpter, and Talking Tom in Sonic the Hedgehog 2 (2022)

Greg Kinnear, James Marsden, and Odessa Young in The Stand (2020)

James Marsden and Jovan Adepo in The Stand (2020)

Greg Kinnear, James Marsden, Odessa Young, Jovan Adepo, and Henrique Zaga in The Stand (2020)

James Marsden, Odessa Young, and Owen Teague in The Stand (2020)

James Marsden and Hamish Linklater in The Stand (2020)

Linda Cardellini and James Marsden in Take 5 With Linda Cardellini and James Marsden (2020)

Jim Carrey, James Marsden, Talking Tom, and Robotnik the Robot in Sonic the Hedgehog (2020)

James Marsden, Maddie, Tika Sumpter, and Talking Tom in Sonic the Hedgehog (2020)

James Marsden and Talking Tom in Sonic the Hedgehog (2020)

Famke Janssen, Halle Berry, Patrick Stewart, Kelly Hu, James Marsden, Ian McKellen, Rebecca Romijn, and Hugh Jackman in X-Men: The Last Stand (2006)

Brad Renfro, Giovanni Ribisi, James Marsden, and Piper Perabo in 10th & Wolf (2006)

Famke Janssen, Halle Berry, Alan Cumming, Patrick Stewart, Kelly Hu, James Marsden, Ian McKellen, Rebecca Romijn, and Hugh Jackman in X-Men (2000)

Robert Hays, Joanna Kerns, and James Marsden in No Dessert, Dad, Till You Mow the Lawn (1994)

Michelle Pfeiffer, John Travolta, Christopher Walken, Queen Latifah, and James Marsden in Hairspray (2007)