- Print ad for Earthjustice Legal Defense Fund (2000)
- (April 15, 2000) Raced in the Toyota Grand Prix of Long Beach Pro/Celebrity Race.
- (1999) Music video: "Crazy" by Britney Spears.
- Recording: "This Is What 'NA NA' Means" (1994)
- Recording: "Peter and the Wolf" (1994)
- Recording: "Sabrina, the Teenage Witch: The Album" (1998)
- CD-ROM: "Nickelodeon Director's Lab" -- Melissa provides on-screen help
- CD-ROM: "Sabrina, the Teenage Witch: Spellbound" (1998) [voice]
- Book: author of the part of The Imperial Princess in "Hans Christian Andersen's The Emperor's New Clothes: an all-star retelling of the classic fairy tale" (1998), published by Harcourt Brace & Company, benefitting the Starbright Foundation
- Writes an advice column for teens in "Teen Beat" magazine
- TV commercial for Jazzy Jewelry (1995)
- TV commercial for Frosted Cheerios (1995)
- Performed in off-Broadway play "Beside Herself" with William Hurt and Calista Flockhart in 1989.
- Play: Imagining Brad (1990)
- Play: The Crucible (1991)
- Magazine Ad for Showstyle (2001)
- TV commercial for Splashy bathtub toys (1980)
- In the summer of 2004, she starred in the Los Angeles play, "Naked TV," and was considered for a lead role in the London production of "When Harry Met Sally," later that year.
- In 1992, co-hosted the premier of Nickelodeon's "Snick" Summer programming line-up.
- TV commercial for Children's Tylenol
- TV commercial for Rice Krispies
- (2013) TV commercial for "Nutrisystem" weight loss program.
- (October 2013) Release of her book, "Melissa Explains It All".
- (2013, 2016) Print ads for the Nutrisystem Weight Loss & Nutrition program.
- (2014) TV commercial for Nutrisystem weight loss program.
- (November 2014 - December 2014) Series of TV commercials, with Anthony Anderson, for Walmart discount department stores.
- (2016) Print ads for Nutrisystem Weight Loss program's "Member's Favorites" frozen 1 Day Diet kits.
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