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Sheila and Joel are married real estate agents who live and work in Santa Clarita, California. When Sheila dies, their lives take a dark turn.

In a biological research company, a son with social problems is forced to work for the company of his father, an extremely eccentric and exotic man to save him from disaster.

In an amoral science-based company, a manager tries to keep control of his scientists while being pressured by his shrewd boss.

Centers on Sean, who must figure out how to parent his 14-year-old daughter, who just moved in, while navigating a temperamental new boss at work.

Short-story writer Andy makes his living by working at a huge faceless company in present-day Chicago, writing technical manuals.

Three 21st century men attempt to channel their inner toughness and redefine what it means to be a "real man."

The misadventures of four paranoid young men whose fear of urban conspiracy leads them to seek counseling in a therapy group run by therapist Claire Garletti.

Two teenage slackers try to make a living at a fast-food place at a local shopping mall while one deals with his dysfunctional family.

Inspired by their co workers, Andy and Jessica decide to engage in some charity work, and soon find themselves competing to win a writing competition at a local prison. Meanwhile, Byron owes Wendy $500 on account of a frivolous bet and wonders how he's ever going to pay up.

When Jessica asks/demands Andy to pick up her nephew Jake after soccer practice, he picks up the wrong kid. Soon the real Jake turns out to be a terror and Andy wishes he'd stuck with Fake Jake instead.

Freddie Pickering, kooky heir to the Pickering legacy, promotes Andy and has him join his life of wealth and debauchery. As this creates a rift between Andy and his friends, he proposes to take them along on a trip to Rio.

Byron makes use of Andy's sarcastic suggestion of introducing a cartoon character into their deep fryer manual, which instantly becomes a huge hit. Not only does Andy resent Byron for stealing his idea, the 'Duh Dog' is also obviously modeled on him. Meanwhile, Keith has become addicted to the deep fryer in question, frying everything he can get his hands on before devouring it.

Wendy asks Andy to read her short story while Byron tries to give a part time stripper/full time psychology student some good advice.

The co-workers grow tired of the cost cutting instigated by the tyrannical Praeger. Byron comes up with a diabolical plan to get revenge.

When co-worker Charlie Rhymer dies of a heart attack, Byron blames himself (and to a lesser extend, so does Jessica). Faced with doing actual work for a change, Keith asks Andy to take Wendy to a Sound of Music This leads Andy's feelings for Wendy to awaken once more.

Byron converts to 'Zumanism' while Jessica goes out with Wendy's unattractive friend, Nick.

Andy gets reacquainted with a hot woman he had a crush on in high school, only to find out she's a bigot. Wendy takes Jessica out for a night on the town on the eve before an important meeting and Jessica subsequently turns into a party animal.

Andy is upset at having to share his office with new employee Byron. He also doesn't like the fact that Keith has slept with the Wendy, the new secretary, on whom Andy has a huge crush.

The co workers are eavesdropping on Jessica's therapist neighbor, who describes her 'cold'. So, Jessica desperately tries to change her ways. Meanwhile Andy hits on Dina, one of the therapist's patients, knowing that she'll begin a relationship with anyone providing he doesn't tell her he loves her.

Andy falls in love with Jessica's maid Irina even though Jessica warns him it will never work out. Wendy is insecure about Keith having no insecurities.

The second episode picks up where the pilot left off. Andy Richter meets his adoring neighbors Phil and Teak, then finds a third man sharing the office with him and Byron. This insufferably optimistic new guy, also called Andy, starts calling Richter 'Big Andy'.

When Andy's attempt to help Wendy with her singing career backfires, she decides to give up her dream entirely. Meanwhile Jessica fools herself into thinking office hunk Milo is not only cute, but also smart and witty.

Andy introduces Jessica to Ben, then tries to prove his theory that Ben and his twin brother are sharing her. Meanwhile, Byron has a festering burn on his back and can't change the bandages on his own.

Andy gets his African-American neighbor Ted a job as a technical writer. Then he gets accused off being a racist after commenting on the Irish.

The entire office spends a weekend in Wisconsin for Ramona from accounting's wedding. Byron is out to score with a bridesmaid while Andy just wants to write. Somehow they end up in bed together.