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Born healthy but did not pass urine for 4 days: How doctors saved a newborn with severe kidney failure and a hidden urinary blockage

Born healthy but did not pass urine for 4 days: How doctors saved a newborn with severe kidney failure and a hidden urinary blockage
(Representative Image)
A baby boy born at 36 weeks appeared healthy at birth, but a silent medical emergency had already begun. Although antenatal scans had detected serious abnormalities in his kidneys and urinary tract and doctors had advised delivery at a tertiary care centre, he was born at a peripheral hospital. By the fourth day of life, the newborn had still not passed urine. When he was rushed to the hospital where doctors found that his kidneys were failing and a life-threatening bloodstream infection had already set in.The newborn was immediately admitted to the Neonatal Intensive Care Unit (NICU), where investigations revealed severe acute kidney injury, with a dangerously elevated serum creatinine of 4.8 mg/dL, along with a fungal bloodstream infection. Without urgent intervention, the baby faced a high risk of permanent kidney damage and serious complications.The Neonatology team acted swiftly. An emergency urinary catheter was inserted to relieve the obstruction, while intensive fluid and electrolyte management, targeted antifungal therapy, respiratory support and nutritional care were initiated simultaneously to stabilise the baby and protect kidney function.
Further investigations identified the underlying cause as Posterior Urethral Valves (PUV)—a rare congenital condition seen only in boys, where abnormal tissue blocks the normal flow of urine from the bladder. The prolonged obstruction had already caused severe bilateral hydronephrosis, a dysplastic polycystic right kidney and a left renal cortical cyst, making preservation of the baby's remaining kidney function the team's highest priority.Over the next two weeks, specialists from Neonatology, Paediatric Nephrology and Paediatric Urology worked together to closely monitor the baby's kidney function, urine output, infection status and overall recovery. Once the fungal infection had been completely treated, blood cultures turned sterile, kidney function improved and the baby became medically stable, he underwent endoscopic fulguration of the posterior urethral valves on Day 21 of life, permanently relieving the obstruction.Following surgery, the baby's recovery was smooth. His urine flow normalised, kidney function continued to improve, he tolerated full oral feeds and was discharged home in a stable condition.Speaking about the case, Dr Sachin Sakharkar, Incharge NICU (Neonatology) and Consultant Pediatrics, KIMS Hospitals, Thane, said, "A newborn is expected to pass urine within the first 24 hours after birth. Failure to do so should never be ignored, as it may indicate a serious urinary tract obstruction requiring immediate medical attention. In this baby, timely urinary decompression, meticulous neonatal intensive care and careful monitoring of kidney function were crucial in preventing irreversible kidney damage. Equally important was ensuring he was stable enough before definitive surgery."Highlighting the importance of antenatal diagnosis and specialised neonatal care," added, Dr Deepika Tiwari, Senior Consultant Pediatrics and Neonatology, KIMS Hospitals, Thane."This case highlights why babies with significant abnormalities detected during pregnancy should ideally be delivered at centres equipped with advanced neonatal intensive care facilities. Early referral, multidisciplinary teamwork and appropriately timed intervention can significantly improve outcomes and preserve long-term kidney function in such newborns."Posterior urethral valves are one of the most common causes of urinary obstruction in newborn boys and, if left untreated, can lead to irreversible kidney damage. Babies who fail to pass urine within the first day of life, or those with abnormalities detected on antenatal scans, should undergo immediate specialist evaluation rather than observation alone.The successful recovery of this 36-week newborn underscores the importance of recognising warning signs early, ensuring timely referral to a tertiary neonatal centre and delivering coordinated multidisciplinary care. In neonatal emergencies, every hour matters—and prompt intervention can change the course of a child's life.
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