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  • 1

    mitoMaker

    mitoMaker - a mitochondria pipeline wrapper script

    ...After various attempts to build different mitochondrial genomes in the lab I studied, a general pipeline started to appear: assemble reads with MIRA or SOAPdenovo-Trans, look for a scaffold/contig that matches a closely-related species, check it to see if all expected genomic features are present (since mitochondria is well conserved), check to see if the assembly might have circularized (since it's a circular DNA). If a feature was missing, or it hasn't circularized, try and assemble again with different assembler parameters (mainly k-mer). Rinse and repeat until the best build is found.
    Downloads: 0 This Week
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  • 2
    A humble approach to simulate an IBM 650 to execute, debug and develop dedicated assembler code. The simulator is implemented in Python2.6+.
    Downloads: 1 This Week
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