The command:
irule -r irods_rule_engine_plugin-python-instance python_rule null null
should succeed if executed by a rodsuser.
In this context, the command line argument python_rule should be taken as the identifier of a python function (a rule) defined in the global namespace of /etc/irods/core.py.
Currently this command only succeeds for a rodsadmin. A rodsuser gets the errorSYS_NO_API_PRIV.