diff --git a/google/cloud/storage/blob.py b/google/cloud/storage/blob.py
index 1380f41bb..c2ff5790e 100644
--- a/google/cloud/storage/blob.py
+++ b/google/cloud/storage/blob.py
@@ -804,7 +804,7 @@ def _extract_headers_from_download(self, response):
 
         digests = {}
         for encoded_digest in x_goog_hash.split(","):
-            match = re.match(r"(crc32c|md5)=([\w\d]+)==", encoded_digest)
+            match = re.match(r"(crc32c|md5)=([\w\d/]+={0,3})", encoded_digest)
             if match:
                 method, digest = match.groups()
                 digests[method] = digest
diff --git a/tests/system/test_system.py b/tests/system/test_system.py
index 3fb701d39..d14187baa 100644
--- a/tests/system/test_system.py
+++ b/tests/system/test_system.py
@@ -910,6 +910,18 @@ def test_upload_blob_owner(self):
         owner = same_blob.owner
         self.assertIn(user_email, owner["entity"])
 
+    def test_blob_crc32_md5_hash(self):
+        blob = self.bucket.blob("MyBuffer")
+        file_contents = b"Hello World"
+        blob.upload_from_string(file_contents)
+        self.case_blobs_to_delete.append(blob)
+
+        download_blob = self.bucket.blob("MyBuffer")
+
+        self.assertEqual(download_blob.download_as_string(), file_contents)
+        self.assertEqual(download_blob.crc32c, blob.crc32c)
+        self.assertEqual(download_blob.md5_hash, blob.md5_hash)
+
 
 class TestUnicode(unittest.TestCase):
     @vpcsc_config.skip_if_inside_vpcsc
diff --git a/tests/unit/test_blob.py b/tests/unit/test_blob.py
index 68011e438..20e20abe4 100644
--- a/tests/unit/test_blob.py
+++ b/tests/unit/test_blob.py
@@ -1476,8 +1476,8 @@ def test_download_as_string_w_response_headers(self):
         self.assertEqual(blob.content_encoding, "gzip")
         self.assertEqual(blob.cache_control, "max-age=1337;public")
         self.assertEqual(blob.storage_class, "STANDARD")
-        self.assertEqual(blob.md5_hash, "CS9tHYTtyFntzj7B9nkkJQ")
-        self.assertEqual(blob.crc32c, "4gcgLQ")
+        self.assertEqual(blob.md5_hash, "CS9tHYTtyFntzj7B9nkkJQ==")
+        self.assertEqual(blob.crc32c, "4gcgLQ==")
 
     def test_download_as_string_w_hash_response_header_none(self):
         blob_name = "blob-name"