Sequentia Biotech

The global probiotics market could reach USD 300 billion by 2033. 📈 As consumer demand for microbiome-based health solutions grows, so does regulatory and commercial pressure on probiotic manufacturers to substantiate their claims. Demonstrating the biological impact of a probiotic intervention is not straightforward. Microbial communities are complex, highly variable between individuals, and compositional shifts can be subtle. This is where high-resolution microbiome analysis becomes essential. But extracting reliable, reproducible insights requires: - Rigorous study design - Accurate taxonomic classification - Robust analytical workflows Not just sequencing data. 💻 Tools like GAIA are helping address this gap by enabling scalable, high-precision microbiome analysis without the traditional bioinformatics bottlenecks. At Sequentia, we support pharma and nutraceutical companies across the full workflow, from study design to data interpretation.

Open-source metagenomic tools are free. But the cost of inconsistent results is not. When the same dataset produces different outputs depending on who runs it, which version of the tool is installed, or which database was last updated, the data cannot be trusted. And data that cannot be trusted cannot support a publication, a regulatory submission, or a business decision. This is one of the most common challenges we see in research and industry teams relying on fragmented open-source pipelines. GAIA is a validated cloud-based metagenomics analysis software that delivers reproducible results — regardless of who runs the analysis, when, or at what scale. Last but not least, GAIA is cost-effective. Our solutions are innovative but always designed to be affordable and scalable. Same input. Same output. Every time. 🔬 Learn more about GAIA: https://lnkd.in/eS3eZakj

Sequencing microbial data has become easy. Interpreting it reliably is still the challenge. The accuracy of taxonomic classification depends heavily on the bioinformatics tools used to analyze those datasets. Different pipelines can produce significantly different results from the same sample. Inconsistent or inaccurate classifications can compromise reproducibility, delay projects, and ultimately increase the risk of project attrition. Two independent benchmarks now confirm GAIA's performance across different sequencing approaches: → 16S rRNA (short-read & long-read amplicon) Across 125 short-read samples, GAIA achieved the highest overall performance with an average F1 score of 0.787, outperforming widely used classifiers such as Mothur, Kraken2 and QIIME2. GAIA also led in long-read amplicon datasets. → Shotgun metagenomics (long-read) In a new benchmark across PacBio HiFi and Oxford Nanopore datasets, GAIA achieved the highest overall F1 score of 0.949, outperforming 11 established methods. GAIA also minimized false positives without compromising recall, thanks to its genome coverage assessment module. GAIA helps laboratories generate more consistent insights from metagenomic data and ultimately reduce the attrition rate associated with unreliable datasets. 🔗 16S rRNA benchmark: https://lnkd.in/en8Ep2i6 🔗 Shotgun metagenomics benchmark: https://lnkd.in/eJXzb_7p

Stop browsing tables. Start conversing with your biological data. Many Shiny dashboards act as data silos—users can filter rows or change plot axes, but they can't ask complex questions across the underlying dataset. We are launching the Applied Bioinformatics Training Course: Integrating LLMs into Shiny Applications for Biological Data Exploration (Oct 5-7, 9:00–13:00 CEST). This 12-hour intensive online course is designed specifically for R users who want to bridge data-rich environments with intuitive, conversational AI interfaces. What you will cover: - Modern Shiny dashboard architecture  - Core LLM mechanics, token management, and secure API configuration - Context-Aware Q&A to inject expression matrices and metadata into an AI's prompt - Scientific Tool-Calling to connect your application to live external literature searches - Controlled "Sandboxing" for safe, AI-assisted plotting and visualization generation 💻 100% Online | ⏳ 12 Hours | 🛠️ Fully Pre-configured Posit Cloud Environment | 👥 Small group format (max. 20 participants) | 📄 Attendance certificate included 🔬 Secure your spot here: https://lnkd.in/eNRgRjVs #ComputationalBiology #Bioinformatics #Shiny #RStats #LLM #GenerativeAI #Biotech #DataScience

Project ANTIOXESSENCE: Revolutionizing Plant Science with Multiomics 🌱 We are proud to announce that our collaborative proposal, ANTIOXESSENCE, has been selected for funding under the European I3-4-BIOFERTILIZERS initiative (Strand 2: Open Innovation). In partnership with Biotech Tricopharming Research, we are pushing the boundaries of sustainable agriculture by developing a novel bio-stimulant designed to enhance the antioxidant properties of Medicinal and Aromatic Plants (MAPs). As the multi-omics partner, we will leverage our bioinformatics expertise to decode the molecular and metabolomic mechanisms of action behind these treatments—ensuring standardized, high-performance ingredients for the next generation of bio-stimulants and biopesticides. This project has received funding from the I3-4-BIOFERTILIZERS project (Agreement No. 101161143) through its Open Call, funded by the European Union under the Interregional Innovation Investments (I3). 🔗 Read the full announcement on our blog: https://lnkd.in/eystPqWr #AgriTech #Bioinformatics #MultiOmics #SustainableFarming #I34Biofertilizers #Innovation #Bioeconomy #PlantScience

📋 Microbial innovation is accelerating, but regulatory expectations are becoming increasingly complex. Today, we officially launch SABIO™ , a specialized solution developed to help companies and laboratories transform genomic data into regulatory-ready safety assessments through a streamlined, EFSA-aligned workflow. From taxonomic identification and AMR screening to mobile genetic element analysis and automated reporting, SABIO™ brings the entire process together in a single platform. ✨ Strengthen your regulatory confidence and accelerate your microbial product development. ➡️ Learn more and explore the solution here: https://lnkd.in/entPggbp 📧 Or reach out to our team at sales@sequentiabiotech.com. #FoodBiotech #Bioinformatics #MicrobialGenomics #FoodInnovation #NovelFoods #Probiotics #GenomeAnalysis #RegulatoryScience #FoodSafety #SequentiaBiotech

Mapping the Future of Brain Metabolism 🚀🔬 The discussions here at the International Conference on Brain Energy Metabolism have been incredible! Our Senior Bioinformatician Alfonso Saera Vila is in the thick of the action, participating in the mentoring sessions and engaging with the brilliant minds here. He is also presenting his latest work: “A Cross-Species Spatial Transcriptomics Framework Integrating Visium and Single-Nucleus RNA-seq to Map Astrocyte Diversity Across Cortical Layers.” His poster demonstrates how we can resolve astrocyte heterogeneity across humans, mice, and cattle by integrating 10x Genomics Visium with advanced deconvolution methods. If you’re participating in the poster sessions or the small group discussions, please come find Alfonso! Let’s keep pushing the boundaries of brain science together. #ICBEM2026 #BrainEnergy #Neuroscience #SequentiaBiotech #SpatialBiology #Astrocyte #Bioinformatics #ScientificExchange #MetabolismResearch

Sequentia Biotech is at #ICBEM2026 🧠⚡ Today marks the start of the International Conference on Brain Energy Metabolism (ICBEM) running from June 29 to July 2. This premier meeting brings together leading researchers to explore the bioenergetics that power the nervous system, and we are excited to be part of the conversations shaping how cellular communication and metabolism drive health and disease. On the ground is Alfonso Saera Vila, our Senior Bioinformatician, who will also be presenting our recent work on the use of spatial transcriptomics to map astrocyte diversity across species. As a team, we are passionate about how high-resolution omics can add new dimensions to neuroscience research. We look forward to engaging with the community throughout the event, sharing ideas, and exploring the future of brain science together. #ICBEM2026 #Neuroscience #SequentiaBiotech #AstrocyteResearch #Bioenergetics #BrainMetabolism #Bioinformatics #ScienceCollaboration

Live from #BarcelonaDebates: Scaling Science and Building Community 🚀🔬 The energy in Barcelona is electric as we dive into day one! Following our great experience at this event last year, we are back for more deep dives into the science that connects the microbiome to human health. We’ve already seen some brilliant opening sessions on how host genetics and immunity are fundamentally reshaped by our microbial residents. Our colleagues Riccardo Aiese Cigliano (CSO), Roberto Malinverni (Senior Bioinformatician), and Jaïr Dilmé Capó (Specialist Bioinformatician) are currently in the thick of the action, moving between poster sessions and panel discussions to engage with the field's leading thinkers. We have brought along a portfolio of related solutions that address the very challenges being discussed today, and they could be of great interest to your ongoing projects. Whether you are here to geek out on the gut-brain axis or the latest in dietary modulation, come find the Sequentia team and let's talk about the future of the microbiome! #BarcelonaDebates #MicrobiomeResearch #SequentiaBiotech #GutBrainAxis #ClinicalDiagnostics #Barcelona #Bioinformatics #OneHealth

Sequentia Biotech is Back for the Barcelona Debates on the Human Microbiome! 🧬 After such a fun and insightful experience last year, we couldn’t miss the chance to return for the 2026 edition! Right here in our home city, this forum has established itself as one of the most important global stages for microbiome research. We are ready to dive back into discussions shaping the field's future, from host genetics to the complex language of microbial metabolites. Representing Sequentia Biotech on the ground this year will be Riccardo Aiese Cigliano (CSO), Roberto Malinverni (Senior Bioinformatician), and Jaïr Dilmé Capó (Specialist Bioinformatician). They are eager to catch up with old colleagues and meet new faces to discuss how the latest scientific trends can be translated into real-world impact. We have a diverse portfolio of related products that align perfectly with the cutting-edge science being presented, and we would love to share how they might support your specific research goals. If you are attending, let’s make this year even better than the last! #BarcelonaDebates #Microbiome #SequentiaBiotech #HumanMicrobiome #Bioinformatics #HealthInnovation #BarcelonaScience