Last week, we were at #ESTIV2026, connecting with the toxicology community and exploring the latest advances in New Approach Methodologies #NAMs. After several days of scientific discussions, poster sessions and industry exchanges, these are some of the key takeaways we bring back to Creatio UB:
🔹 The continued consolidation of 3D and iPSC-derived models as key tools for human-relevant research.
🔹 A strong focus on neurotoxicity and nervous system models, highlighting the growing interest in more predictive approaches for assessing brain health and disease.
🔹 Increasing adoption of functional readouts and advanced phenotyping technologies, including electrophysiology, neuronal network analysis, High Content Imaging and Cell Painting.
Among the most interesting discussions were those addressing the validation and regulatory implementation of non-animal methodologies, including iPSC-based models, Organ-on-Chip technologies and approaches for developmental and reproductive toxicity (DART) assessment.
The poster sessions also showcased exciting advances, from 3D neuromuscular junction models and neuronal co-culture systems to 3D brain models for developmental toxicity studies and digital tools designed to improve reproducibility in vitro.
Beyond the scientific programme, the exhibition area provided valuable opportunities to explore new technologies and exchange ideas with companies developing innovative solutions for stem cell culture, functional assays and advanced in vitro platforms.
We leave ESTIV with new ideas, stimulating discussions and several promising connections for future collaborations.
A big thank you to everyone we met along the way. It's always inspiring to be part of a community working towards more predictive, human-relevant and sustainable approaches in toxicology.
#ESTIV2026 #Neuroscience #InVitroToxicology #OoC
Universitat de Barcelona Institute of Neurosciences of the University of Barcelona Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)