Immune thrombocytopenic purpura: Difference between revisions

 

== Epidemiology ==

 

The incidence of ITP is estimated at 50&ndash;100 new cases per million per year, with children accounting for half of that amount.&nbsp; At least 70 percent of childhood cases will end up in remission within six months, whether treated or not.<ref name="pmid15494875">{{cite journal |author=Watts RG |title=Idiopathic thrombocytopenic purpura: a 10-year natural history study at the children's hospital of alabama |journal=Clinical pediatrics |volume=43 |issue=8 |pages=691–702 |year=2004 |pmid=15494875|doi=10.1177/000992280404300802}}</ref><ref name="pmid17460024">{{cite journal |author=Treutiger I, Rajantie J, Zeller B, Henter JI, Elinder G, Rosthøj S |title=Does treatment of newly diagnosed idiopathic thrombocytopenic purpura reduce morbidity? |journal=Arch. Dis. Child. |volume=92 |issue=8 |pages=704–7 |year=2007 |pmid=17460024 |doi=10.1136/adc.2006.098442}}</ref><ref name="pmid17352309">{{cite journal |author=Ou CY, Hsieh KS, Chiou YH, Chang YH, Ger LP |title=A comparative study of initial use of intravenous immunoglobulin and prednisolone treatments in childhood idiopathic thrombocytopenic purpur |journal=Acta paediatrica Taiwanica &#61; Taiwan er ke yi xue hui za zhi |volume=47 |issue=5 |pages=226–31 |year=2006 |pmid=17352309 |doi=}}</ref>&nbsp; Moreover, a third of the remaining chronic cases remitted during follow-up observation, and another third ended up with only mild thrombocytopenia (defined as a platelet count above 50,000).<ref name="pmid15494875"/>