File:Loss of Heterozygosity.png
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Loss_of_Heterozygosity.png (687 × 448 pixels, file size: 10 KB, MIME type: image/png)
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[edit]DescriptionLoss of Heterozygosity.png | Loss of heterozygosity means that the another allele of the gene is lost. Then only already mutated allele is left. M=maternal chromosome, P=paternal chromosome. White circle=normal allele, black circle=mutated allele, orange circle=point mutation in the allele, red circle=allele is inactivated due to the epigenetic reason. Arrows show different malicious genetic happenigs. In A-C cases the loss of heterozygosity of the gene has happened and mechanisms are different. A=The another chromosome has been lost, B=The malicious recombination has happened and C=The deletion of the normal allele has happened. In D and E cases both alleles have been inactivated, but the heterozygosity remains. |
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Source | Own work |
Author | Teemu Pelkonen |
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[edit]Public domainPublic domainfalsefalse |
I, the copyright holder of this work, release this work into the public domain. This applies worldwide. In some countries this may not be legally possible; if so: I grant anyone the right to use this work for any purpose, without any conditions, unless such conditions are required by law. |
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Date/Time | Thumbnail | Dimensions | User | Comment | |
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current | 13:32, 14 May 2008 | 687 × 448 (10 KB) | Teemu Pelkonen~commonswiki (talk | contribs) | {{Information |Description=Loss of heterozygosity means that the another allele of the gene is lost. Then only already mutated allele is left. M=maternal chromosome, P=paternal chromosome. White circle=normal allele, black circle=mutated allele, orange ci |
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