Frontiers - Infectious Disease

🌍 The environment is one of the least monitored drivers of antimicrobial resistance — and that needs to change. Pharmaceuticals flushed into waterways, microplastics accumulating in agricultural soils, pesticide residues exerting pressure on microbial communities — the environments we’ve altered are quietly reshaping the global resistome. Our Research Topic, Emerging Pollutants and the Environmental Resistome: Microbial Responses and Implications for Human Health, in Frontiers in Cellular and Infection Microbiology, is bringing together the research that makes that invisible process visible. What makes this space so compelling is the chain of consequence it reveals. Resistance doesn’t emerge in a vacuum — it evolves under pressure, spreads through horizontal gene transfer, and travels from contaminated soil and water into food chains, clinical settings, and human populations. Understanding that journey, and where it can be interrupted, is exactly the kind of science that moves policy as well as knowledge. The submission deadline is 23 October 2026, and we welcome contributions across a wide range of formats — from original research and metagenomics-driven studies to reviews, perspectives, and opinion pieces. If your work sits at the crossroads of environmental microbiology and infectious disease, we’d love to have it in this collection. 🔗 https://lnkd.in/eyxU6UdE #AntimicrobialResistance #OneHealth #EnvironmentalMicrobiology #Resistome #OpenAccess #FrontiersIn

🦟 Call for Papers: Vector-Borne Diseases and Transmission Dynamics in Changing Climates Malaria, dengue, Zika, leishmaniasis, Lyme disease - the vectors that spread them are on the move, and climate change is rewriting the rules of transmission. This Frontiers Research Topic brings together molecular, ecological, and epidemiological perspectives to explore: ✅ Pathogen-vector interactions at tissue barriers (midgut, salivary glands) ✅ The role of vector microbiomes in disease transmission ✅ Genetic and epigenetic drivers of vector competence ✅ Climate change’s impact on vector ecology and distribution ✅ Modeling transmission dynamics under future climate scenarios ✅ Novel vector control strategies (microbiome engineering, transmission-blocking vaccines) ✅ Field case studies linking ecology, climate, and disease risk Contributing to global health targets under SDG 3, we welcome submissions from researchers across disciplines working on any vector-borne disease system. 📅 Submission deadline: 16 September ➡️ Submit your research: https://lnkd.in/dkxZQK_2

🔬 New Research Topic Now Open for Submissions! We’re pleased to announce the launch of “Latent Tuberculosis Infection: New Insights into Persistence, Detection, and Prevention” in Frontiers in Tuberculosis. An estimated one-quarter of the world’s population carries Mycobacterium tuberculosis in a dormant state, yet the mechanisms enabling its persistence, immune evasion, and eventual reactivation remain incompletely understood — a gap that continues to limit progress on both diagnostics and prevention. This collection welcomes contributions across three key areas: 🧫 The molecular and immunological basis of bacterial dormancy and persistence; 🩺 Novel biomarkers and diagnostic platforms for risk stratification; 💊 Advances in preventive therapies, host-directed treatments, and vaccine strategies. Led by Topic Editors Hemant Joshi, Ph.D. (University of California San Francisco) and Deeksha Tripathi (Central University of Rajasthan), the Research Topic accepts Original Research, Reviews, Mini Reviews, Perspective, and Systematic Review articles. We welcome researchers working on TB persistence, detection, or prevention to contribute to this collection. 🔗 Check the scope and submit here: https://lnkd.in/dDmY4Dkm #TuberculosisResearch #LatentTB #OpenAccess #Immunology #Microbiology #GlobalHealth

🚨Call for Papers🚨 We are happy to announce that our Research Topic, “Innovative Technologies Against Malaria: Metabolomics, Systems Biology, and Nanotechnology” is now open for submissions! We invite researchers to contribute findings on: ✅ Metabolic pathways driving Plasmodium growth, drug resistance, and host-parasite interactions ✅ Systems-based and computational modeling of parasite biology and drug response ✅ Nanotechnology innovations for targeted drug delivery, diagnostics, and vector control Help us translate cutting-edge biochemical and computational insights into practical strategies for malaria control and elimination. We look forward to seeing your cutting-edge work! Questions? please contact us at: malaria@frontiersin.org 👉 Read the full scope & submit: https://lnkd.in/gUhctP9s #Malaria #Metabolomics #SystemsBiology #Nanotechnology #Parasitology #GlobalHealth

Oral health and women’s systemic immunity don’t share many stages. They have separate clinical homes, separate research communities, and — until recently — separate funding streams. What’s shifted is the evidence base: mechanistic studies are now making a case that’s harder to dismiss, and reproductive and perinatal immunology is increasingly receptive to data that arrives from an unexpected direction. That convergence is exactly the kind of moment a collection like this is built for. For researchers sitting on longitudinal cohort data, interventional trial results, or multi-omics readouts that touch this intersection, the window to contribute is closing. The question of whether oral inflammation actively shapes systemic immune tone — rather than simply tracking alongside it — is one the field is ready to answer, and the studies that address it with temporal and mechanistic rigour are the ones that will move the needle. Pregnancy outcomes, infant immune development, hormonal modulation of the oral microbiome: all of it is within scope when it’s anchored to a defined immune pathway. Frontiers in Cellular and Infection Microbiology — don’t leave this work siloed. Submissions are still open, but not for long. 👉 More information & Submit: https://lnkd.in/ecacsib8

From Immune Privilege to Immune Signatures: Innate–Adaptive Crosstalk in Ocular Infection and Inflammation Ocular infections remain one of the most challenging areas in immunology, precisely because the eye has evolved to protect vision at the cost of a dampened immune response. Understanding how innate and adaptive immunity coordinate — or fail to coordinate — when pathogens breach this privileged environment is critical for improving outcomes in patients facing viral, bacterial, fungal, and parasitic threats to sight. This Research Topic has already generated strong engagement within the field, reaching 2,238 views and downloads since launch — a clear signal that researchers see real value in bringing together mechanistic, translational, and clinical perspectives on this subject. Contributions exploring immune signatures, biomarkers, and host-directed therapeutic strategies are especially timely as the field moves toward more precise, infection-specific approaches to managing ocular inflammatory disease. We’re inviting researchers working across ocular immunology, infectious disease, and translational diagnostics to contribute before the submission deadline on November 20. If your work touches on host–pathogen interactions, barrier dysfunction, or immune cell trafficking in the eye, this is a great opportunity to share your findings with an engaged and growing readership.  Read more and submit: https://lnkd.in/eh3X8qMf

👁️ Why ocular infection immunology deserves more attention than it gets. Sight is one of our most vital senses, yet the immunology of ocular infection remains a relatively underexplored frontier. The eye’s immune privilege — long considered a protective feature — can become a double-edged sword during active infection, limiting inflammatory damage but also potentially shielding pathogens from clearance. As rates of infectious eye disease continue to affect millions globally, the need for clearer insight into how host immunity responds, adapts, and sometimes fails in the ocular environment has never been more pressing. Defining immune signatures in ocular fluids and tissues, understanding microbial persistence and immune evasion, and identifying the tipping point between protective immunity and immunopathology are questions with real clinical stakes — from improving diagnostics in uveitis and keratitis to informing treatment strategies that combine antimicrobial and immunomodulatory approaches. Research in this space has the potential to reshape how we manage infectious causes of visual morbidity across bacterial, viral, fungal, and parasitic disease. Our Research Topic in Frontiers in Cellular and Infection Microbiology is actively welcoming submissions on exactly these questions. If your work sits at the intersection of infection, immunity, and the eye — whether mechanistic, translational, or clinical — there is still time to contribute. More information & submit: https://lnkd.in/eh3X8qMf

Millions of people fall ill with tuberculosis every year, and yet many never reach treatment in time - not because a cure doesn’t exist, but because the path to it is broken. TB remains the leading cause of death from a single infectious disease worldwide, disproportionately affecting low- and middle-income countries (LMICs). Where do patients get lost between their first symptom and starting treatment? What role do stigma, health system fragmentation, and gender norms play in these delays? And what interventions actually shorten the care cascade? We’re very excited to share that these are the questions at the heart of our new Research Topic in Frontiers in Tuberculosis: “From Symptoms to Treatment: Patient Pathways and Delays in TB Care in LMICs.” Our Topic Editors Dr. Janmejaya Samal (SRM Institute of Science and Technology, India) and Dr. Jeremiah Chikovore (Human Sciences Research Council, South Africa) welcome contributions on, but not limited to: - Demand-side (patient-related) and supply-side (health system) delays - Patient journeys across public, private, and informal healthcare providers - Social determinants of TB across the care cascade - Stigma, trust, and lived experiences influencing delays - Innovations in pathway analysis, network mapping, and systems approaches - Policy, programmatic, and health system interventions to reduce delays - Comparative and multi-country analyses, including India-focused studies 📅 Manuscript deadline: 12 February 2027 🔗 Learn more and register your interest: https://lnkd.in/em2mdhcV Any questions? Our team at tuberculosis@frontiersin.org is happy to help! #Tuberculosis #TBCare #GlobalHealth #LMICs #OpenAccess #FrontiersInTuberculosis #PublicHealth #HealthEquity #EndTB

📢 Call for Papers | Immune Cell Remodeling and Reprogramming in Infectious Diseases: Single-Cell and Spatial Insights toward Precision Therapeutics Infectious disease outcomes depend not only on pathogen characteristics but also on how the host immune system adapts during infection. Functional, metabolic, and epigenetic reprogramming of immune cells can shape pathogen clearance, disease persistence, immune-mediated damage, and therapeutic response. Advances in single-cell, spatial, and multi-omics technologies now allow researchers to map immune cell diversity and interactions at unprecedented resolution. Translating these insights into reliable biomarkers and host-directed therapies, however, remains a key challenge. This Research Topic welcomes contributions on: 🧬 Immune cell remodeling and cellular reprogramming during infection 🔬 Monocyte–macrophage plasticity, T-cell exhaustion, and B-cell or NK-cell dysfunction 🦠 Dendritic-cell reprogramming, neutrophil heterogeneity, and trained immunity 🧪 Metabolic and epigenetic adaptation of immune cells 🗺️ Single-cell and spatial mapping of immune states, trajectories, and cell–cell communication 🦠 Microbiome–immune interactions, including biofilm-associated infections 🎯 Immune biomarkers, precision therapeutics, and host-directed interventions 🏥 Longitudinal cohorts, clinical trials, real-world evidence, and implementation science 🤖 AI-based approaches supporting clinical translation We invite basic, translational, computational, and clinical studies that place host immune remodeling at the center of infectious disease research. 📩 Submit your manuscript here: https://lnkd.in/gSZ6Kbj2 #InfectiousDiseases #SingleCell #SpatialOmics #MultiOmics #Immunology #ImmuneRemodeling #PrecisionMedicine #HostDirectedTherapy #Biomarkers #TranslationalResearch #FrontiersInCellularAndInfectionMicrobiology

While much recent attention has focused on long COVID, millions of patients globally continue to struggle with other persistent post-infectious sequelae, such as Post-Treatment Lyme Disease Syndrome, chronic post-viral fatigue, and post-bacterial autoimmune conditions. These complex syndromes present persistent diagnostic and therapeutic challenges due to the lack of standardized clinical criteria and validated biomarkers. To address these critical gaps, Frontiers in Cellular and Infection Microbiology has launched a new Research Topic dedicated to advancing clinical diagnostics and immunological profiling for post-acute infectious syndromes. This collection serves as a dedicated forum for researchers developing and validating novel molecular, serological, and immunological assays. By prioritizing studies that translate basic microbiology and immunology into actionable clinical tools, we aim to establish robust tracking methods, discover reliable inflammatory biomarkers, and refine autoantibody profiling. Shifting the focus from purely mechanistic models to practical diagnostic translation will equip clinicians with the objective evidence required to risk-stratify patients and monitor immune responses during therapeutic interventions. We are privileged to have this Research Topic led by an expert international editorial team, including Juan Sebastian Izquierdo-Condoy and Esteban Ortiz-Prado from the University of the Americas (Ecuador), along with Manuel Colomé-Hidalgo from the Universidad Autónoma de Santo Domingo (Dominican Republic). We invite immunologists, clinical microbiologists, and diagnostic researchers to contribute their latest findings and help shape the future of post-infectious clinical care. Submissions are now open, and we welcome you to join this collaborative effort to improve patient outcomes worldwide. More information & submit: https://lnkd.in/eVuFKSMs